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Table 6 Late toxic reactions

From: Efficacy of concurrent chemoradiotherapy plus Endostar compared with concurrent chemoradiotherapy in the treatment of locally advanced nasopharyngeal carcinoma: a retrospective study

Adverse event CCRT + E
(n = 43)
CCRT
(n = 45)
P value for events
Grade 1 and 2
P value for events
Grade 3 and 4
1 + 2 3 4 1 + 2 3 4
Limitation of mouth opening 1 (2.3) 0 (0) 0 (0) 1 (2.2) 0 (0) 0 (0) 1.000
Decreased vision 1 (2.3) 0 (0) 0 (0) 2 (4.4) 0 (0) 0 (0) 1.000
Hearing loss 6 (14.0) 0 (0) 0 (0) 6 (13.3) 2 (4.4) 0 (0) 0.932 0.495
Temporal lobe necrosis 1 (2.3) 0 (0) 0 (0) 1 (2.2) 0 (0) 0 (0) 1.000
Subcutaneous fibrosis 1 (2.3) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0.489
Dry mouth 5 (11.6) 0 (0) 0 (0) 3 (6.7) 0 (0) 0 (0) 0.661
Cranial nerve palsy 3 (7.0) 0 (0) 0 (0) 2 (4.4) 0 (0) 0 (0) 0.958
Cardiac dysfunction 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0)
  1. Data are n (%)