Skip to main content

Table 6 Late toxic reactions

From: Efficacy of concurrent chemoradiotherapy plus Endostar compared with concurrent chemoradiotherapy in the treatment of locally advanced nasopharyngeal carcinoma: a retrospective study

Adverse event

CCRT + E

(n = 43)

CCRT

(n = 45)

P value for events

Grade 1 and 2

P value for events

Grade 3 and 4

1 + 2

3

4

1 + 2

3

4

Limitation of mouth opening

1 (2.3)

0 (0)

0 (0)

1 (2.2)

0 (0)

0 (0)

1.000

Decreased vision

1 (2.3)

0 (0)

0 (0)

2 (4.4)

0 (0)

0 (0)

1.000

Hearing loss

6 (14.0)

0 (0)

0 (0)

6 (13.3)

2 (4.4)

0 (0)

0.932

0.495

Temporal lobe necrosis

1 (2.3)

0 (0)

0 (0)

1 (2.2)

0 (0)

0 (0)

1.000

Subcutaneous fibrosis

1 (2.3)

0 (0)

0 (0)

0 (0)

0 (0)

0 (0)

0.489

Dry mouth

5 (11.6)

0 (0)

0 (0)

3 (6.7)

0 (0)

0 (0)

0.661

Cranial nerve palsy

3 (7.0)

0 (0)

0 (0)

2 (4.4)

0 (0)

0 (0)

0.958

Cardiac dysfunction

0 (0)

0 (0)

0 (0)

0 (0)

0 (0)

0 (0)

  1. Data are n (%)