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Table 6 Correlation radiation dose and ultrasound parameter differences between irradiated and control side

From: Assessing radiation-induced carotid vasculopathy using ultrasound after unilateral irradiation: a cross-sectional study

Parameter Location Time point Regression coeff. RT dose (95% CI)1 P Corrected regression coeff. RT dose (95% CI)2 p
ΔIMT (mm) Distal CCA Diastole  − 0.001 (− 0.003 to 0.002) 0.60  − 0.001 (− 0.004 to 0.001) 0.35
ICA 0.000 (0.000 to 0.001) 0.20 0.000 (− 0.001 to 0.001) 0.60
ΔPWV (m/s) Mid-CCA Begin-systole 0.040 (− 0.032 to 0.111) 0.26 0.065 (− 0.025 to 0.154) 0.15
End-systole 0.052 (− 0.005 to 0.110) 0.07 0.048 (− 0.005 to 0.101) 0.07
ΔSWV (m/s) Proximal CCA Averaged over cardiac cycle A: 0.009 (− 0.025 to 0.043) 0.61 0.001 (− 0.038 to 0.040) 0.95
P: 0.024 (− 0.007 to 0.055) 0.12 0.021 (− 0.017 to 0.060) 0.26
Mid-CCA A: 0.003 (− 0.023 to 0.029) 0.79 0.017 (− 0.015 to 0.048) 0.28
P: 0.011 (− 0.026 to 0.047) 0.55 0.022 (− 0.025 to 0.069) 0.34
Distal CCA A: − 0.004 (− 0.028 to 0.020) 0.75 0.005 (− 0.016 to 0.027) 0.60
P: − 0.006 (− 0.032 to 0.020) 0.66 0.005 (− 0.019 to 0.029) 0.67
ICA A: 0.009 (− 0.024 to 0.043) 0.57  − 0.001 (− 0.051 to 0.049) 0.96
P: 0.001 (− 0.022 to 0.024) 0.93  − 0.007 (− 0.110 to 0.024) 0.63
  1. RT radiotherapy, CI confidence interval, IMT intima-media thickness, PWV pulse wave velocity, SWV shear wave velocity, CCA common carotid artery, ICA internal carotid artery, A Anterior, P posterior
  2. 1Linear regression coefficient per Gray dose difference
  3. 2Linear regression coefficient per Gray dose difference corrected for age, systolic blood pressure during ultrasound examination, number of cardiovascular risk factors, and concomitant chemotherapy