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Table 4 Intra- and interobserver reproducibility of the entire process (acquisition including analysis) and of solely the analysis of ultrasound measurements

From: Assessing radiation-induced carotid vasculopathy using ultrasound after unilateral irradiation: a cross-sectional study

Parameter

Location

Time point

Process (n = 26)

Analysis (n = 10)

Intra-observer ICC (95% CI)

Intra-observer ICC (95% CI)

Inter-observer ICC (95% CI)

IMT (mm)

Distal CCA

Diastole

0.972 (0.956–0.983)

0.930 (0.833–0.972)

0.939 (0.853–0.976)

ICA

0.657 (0.510–0.778)

0.570 (0.167–0.726)

0.272 (− 0.100–0.607)

PWV (m/s)

Mid-CCA

Begin-systole

0.725 (0.554–0.852)

n/a1

n/a1

End-systole

0.707 (0.551–0.828)

n/a1 

n/a1 

SWV (m/s)

Proximal CCA

Averaged

A: 0.873 (0.804–0.922)

A: 0.998 (0.994–0.999)

A: 0.991 (0.977–0.997)

P: 0.745 (0.628–0.837)

P: 0.995 (0.979–0.998)

P: 0.978 (0.867–0.994)

Mid-CCA

A: 0.919 (0.874–0.950)

A: 0.997 (0.992–0.999)

A: 0.995 (0.986–0.998)

P: 0.876 (0.811–0.923)

P: 0.997 (0.984–0.999)

P: 0.986 (0.885–0.996)

Distal CCA

A: 0.899 (0.846–0.937)

A: 0.997 (0.992–0.999)

A: 0.996 (0.989–0.998)

P: 0.881 (0.820–0.926)

P: 0.998 (0.984–0.999)

P: 0.992 (0.976–0.997)

ICA

A: 0.916 (0.866–0.950)

A: 0.994 (0.986–0.998)

A: 0.988 (0.970–0.995)

P: 0.859 (0.773–0.919)

P: 0.974 (0.928–0.990)

P: 0.963 (0.898–0.986)

  1. IMT intima-media thickness, PWV pulse wave velocity, SWV shear wave velocity, CCA common carotid artery, ICA internal carotid artery, ICC intraclass correlation coefficient, CI confidence interval, A anterior, P posterior
  2. 1Automatic analysis by Aixplorer system so independent of user interpretation