Table 2 Summary of dosimetric parameters of DCAT and VMAT plans

Median target coverage

98.9%

99.1%

NS

Range

95.8%-100%

96.3–100%

Paddick conformity index

Mean

0.72 (0.09)

0.67 (0.10)

0.005

Range

0.52–0.86

0.50–0.85

Gradient index

Mean

4.75

5.61

< 0.0001

Range

3.45–7.13

3.64–8.37

PTV dose (Gy)

Mean (SD)

23.3 (0.23)

24.0 (0.8)

0.0001

Median

23.3

24.0

Range

22.9–23.9

22.5–25.4

PTV D2%

Mean (SD)

25.5 (0.4)

26.3 (1.2)

0.001

Median

25.4

26.5

Range

25.4–27

23.4–28.6

Brain

0.0001

Mean dose (SD)

2.64 (1.3)

3.01 (1.5)

Median dose (SD)

2.37

2.74

Range

0.65–5.62

0.55–5.85

V12Gy

< 0.0001

Mean (SD)

14.7 (11.5)

21.8 (17.2)

Median

13.6

18.5

Range

1.87–45.9

2.2–62.3

V10Gy

< 0.0001

Mean (SD)

22.3 (17.4)

33.7 (28.9)

Median

17.4

27.9

Range

2.6–74.2

2.9–100.6

V8Gy

< 0.0001

Mean (SD)

39.4 (38.1)

59.8 (52.8)

Median

26.6

46.0

Range

3.7–157

4.6–184

V5Gy

< 0.0001

Mean (SD)

141.2 (164.6)

211.0 (212.7)

Median

73.2

142.3

Range

8.18–701.8

11.3–707.8

Right hippocampus

0.0005

Mean dose (SD)

2.6 (1.7)

3.2 (2.2)

Median dose

1.9

2.2

Range

0.6–6.9

0.6–8.6

Left hippocampus

0.0001

Mean dose (SD)

2.7 (1.3)

3.4 (1.9)

Median dose

2.1

2.7

Range

0.5–6.4

0.5–9.8