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Table 2 Summary of dosimetric parameters of DCAT and VMAT plans

From: Single-isocenter multiple-target stereotactic radiosurgery for multiple brain metastases: dosimetric evaluation of two automated treatment planning systems

Parameter DCAT VMAT p
Median target coverage 98.9% 99.1% NS
Range 95.8%-100% 96.3–100%  
Paddick conformity index
Mean 0.72 (0.09) 0.67 (0.10) 0.005
Range 0.52–0.86 0.50–0.85  
Gradient index
Mean 4.75 5.61 < 0.0001
Range 3.45–7.13 3.64–8.37  
PTV dose (Gy)
Mean (SD) 23.3 (0.23) 24.0 (0.8) 0.0001
Median 23.3 24.0  
Range 22.9–23.9 22.5–25.4  
PTV D2%
Mean (SD) 25.5 (0.4) 26.3 (1.2) 0.001
Median 25.4 26.5  
Range 25.4–27 23.4–28.6  
Brain    0.0001
Mean dose (SD) 2.64 (1.3) 3.01 (1.5)  
Median dose (SD) 2.37 2.74  
Range 0.65–5.62 0.55–5.85  
V12Gy    < 0.0001
Mean (SD) 14.7 (11.5) 21.8 (17.2)  
Median 13.6 18.5  
Range 1.87–45.9 2.2–62.3  
V10Gy    < 0.0001
Mean (SD) 22.3 (17.4) 33.7 (28.9)  
Median 17.4 27.9  
Range 2.6–74.2 2.9–100.6  
V8Gy    < 0.0001
Mean (SD) 39.4 (38.1) 59.8 (52.8)  
Median 26.6 46.0  
Range 3.7–157 4.6–184  
V5Gy    < 0.0001
Mean (SD) 141.2 (164.6) 211.0 (212.7)  
Median 73.2 142.3  
Range 8.18–701.8 11.3–707.8  
Right hippocampus    0.0005
Mean dose (SD) 2.6 (1.7) 3.2 (2.2)  
Median dose 1.9 2.2  
Range 0.6–6.9 0.6–8.6  
Left hippocampus    0.0001
Mean dose (SD) 2.7 (1.3) 3.4 (1.9)  
Median dose 2.1 2.7  
Range 0.5–6.4 0.5–9.8  
  1. DCAT Dynamic Conformal Arc Therapy, VMAT Volumetric Target Volume, PTV Planning Target Volume, PTV D2% dose received by 2% of PTV, SD Standard deviation, V5-12 Gy volumes of healthy brain (brain-gross tumor volume) receiving 5,8,10, and 12 Gy