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Table 2 Radiation dose details and acute toxicities

From: Encouraging early outcomes with image guided pencil beam proton therapy for cranio-spinal irradiation: first report from India

  CSI (Total) CSI (> 14 years) CSI (< 14 years)
n 40 (100%) 9 (22.5%) 31 (77.5%)
PTV CSI D95 (Avg) 97.4% 99.2% 96.6%
CTV CSI D98 (Avg) 98.6% 99.1% 97.2%
Lens (D max) Avg 2.96 Gy (1.76%) 2.96 Gy (1.76%) 2.96 Gy (1.76%)
Cornea (D Mean) Avg 1.68 Gy (1.34%) 1.68 Gy (1.34%) 1.68 Gy (1.34%)
Cochlea (D Max) Avg 27.3 Gy (93.5%) 27.3 Gy (93.5%) 27.3 Gy (93.5%)
Parotids (D mean) Avg 10.67 Gy (4.63%) 0.44 Gy (0.01%) 12.6 (37%)
Esophagus (D Max) Avg 20.31 Gy (61.6%) 0.00 (0) 27.7 Gy (84%)
Lung (D mean) Avg 0.65 Gy (0.01%) 1.85 Gy (0.07%) 3.22 Gy (0.09%)
Kidney (D mean) Avg 1.85 Gy (0.08%) 2.05 Gy (0.09%) 7.78 Gy (0.23%)
Heart (D mean) Avg 0 0 0
Bowel Bag (D mean) Avg 0.18 Gy (0.007%) 0.01 Gy (0) 0.21 Gy (0.006%)
Liver (D mean) Avg 0 0 0
Gonads (D mean) Avg 0 0 0
Dermatitis
 Grade 1
 Grade 2
 Grade 3
20 (50%)
20 (50%)
0
4 (44.4%)
5 (56.6%)
0
17 (54.8%)
14 (45.2%)
0
Mucositis
 Grade 1
 Grade 2
 Grade 3
8 (20%)
2 (5%)
1 (2.5%)
1 (11.1%)
1 (11.1%)
0
7 (22.5%)
2 (6.5%)
1 (3.2%)
Weight loss
 Grade 1
 Grade 2
3 (7.5%)
0
0
0
3 (9.6%)
0
Nausea
 Grade 1
 Grade 2
6 (15%)
0
0
0
6 (19.4%)
0
Anorexia
 Grade 1
 Grade 2
7 (17.5%)
0
1 (11.1%)
0
6 (19.4%)
0
Hospital admissions during treatment 5 (12.5%) Nil 5 (16.1%)
Average hospital stay = 2.4 days
Treatment gap during treatment 3 (7.5%) Nil 3 (9.6%)
  Average treatment gap = 2 days