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Table 1 Patient and tumor characteristics (n = 100)

From: Locally advanced NSCLC: a plea for sparing the ipsilateral normal lung—prospective, clinical trial with DART-bid (dose-differentiated accelerated radiation therapy, 1.8 Gy twice daily) by VMAT

Age, years, median

68 (43 – 88)

Sex: m/f, n

67 / 33

Weight loss > 5%/3 month, n (%)

29 (29)

Karnofsky Index, n (%)

  100

14 (14)

  90

26 (26)

  80

37 (37)

  70

12 (12)

  60

9 (9)

  50

2 (2)

COPD as comorbidity, n (%)

  Grade 2

34 (34)

    3

17 (17)

    4

2 (2)

Stage–grouping (UICC/ AJCC 8th edition), n (%)

  II A

2 (2)

  II B

10(10)

  III A

27 (27)

  III B

43 (43)

  III C

14 (14)

  IV A*

4 (4)

Histology/cytology, n (%)

  Adenocarcinoma

45 (45)

  Squamous cell carcinoma

51 (51)

  NSC—n. o. s

4 (4)

Tumor localisation, n (%)

  Central

37 (37)

  Peripheral

60 (60)

  Primary not detectable

3 (3)

Gross tumor volume, ccm, median (range)

  Group 1 (n = 17)

18 (4 – 47)

  Group 2 (n = 52)

45 (12 – 218)

  Group 3 (n = 20)

104 (46 – 255)

  Group 4 (n = 8)

241 (189 – 387)

  1. *Patients with separate tumor nodule(s) in a contralateral lobe (M1a)
  2. COPD = Chronic obstructive pulmonary disease, UICC = Union for international cancer control, AJCC = American Joint Commission on Cancer; FDG-PET = 18-fluorodeoxyglucose-positron emission tomography; NSC—n.o.s. = Non-small cell—not otherwise specified