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Table 3 T4-defining features on a per patient basis at initial diagnosis assessed on computed tomography, positron emission tomography/ computed tomography and with the help of endobronchial ultrasound: (I) Vertebral body; (II) Diaphragm; (III) Esophagus; (IV) Recurrent laryngeal nerve; (V) Heart; (VI) Trachea; (VII) Carina; (VIII) Tumor size > 7 cm; (IX) Mediastinum; (X) Great vessels

From: Long-term survival of patients with central or > 7 cm T4 N0/1 M0 non-small-cell lung cancer treated with definitive concurrent radiochemotherapy in comparison to trimodality treatment

N of patients Single criterion Vertebral body Diaphragm T4 defining features
Esophagus Recurrent laryngeal nerve Heart Trachea Carina Tumor size > 7 cm Mediastinum Great vessels
Vertebral body
Diaphragm
Esophagus
Recurrent laryngeal nerve 1 1 1
Heart 1 2 1 1 1
Trachea 4 2 4 3
Carina 2 11 2 10 10
Tumor size > 7 cm 1 2 18 17 14
Mediastinum 1 1 4 10 17 38 32
Great vessels 5 1 1 3 10 14 32 39