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Table 2 The detail treatment and therapeutic evaluation of 8 patients

From: Stereotactic body radiotherapy extends the clinical benefit of PD-1 inhibitors in refractory recurrent/metastatic nasopharyngeal carcinoma

ID

PD 1 inhibitors

SBRT

Therapeutic evaluation

Dose

Radiation sites

PD-1inhibitor alone

Radiated lesions

Non-Radiated lesions

1

Nivolumab (5 cycles)

25 Gy/5Fx

Progressive lesions

PD

PR

PD

2

Pembroizumab

(6 cycles)

30 Gy/6Fx

All visible lesions

PD

CR

NA

3

Nivolumab (5 cycles)

30 Gy/6Fx

Progressive lesions

PD

CR

Unevaluable

4

Nivolumab (14 cycles)

36 Gy/6Fx

Main lesions

SD

PR

SD

5

Nivolumab (11 cycles)

30 Gy/6Fx

Main lesions

SD

PR

SD

6

Nivolumab (6 cycles)

30 Gy/6Fx

All visible lesions

PD

CR

NA

7

Nivolumab (6 cycles)

No

NA

CR

NA

NA

8

Nivolumab (9 cycles)

30 Gy/6Fx

Progressive lesions

PD

PR

Unevaluable

  1. CR: complete response; PR: partial response; SD: stable disease; PD: progressive disease; NA: not assessed