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Table 4 Multivariate analysis of the risk factors for CSS (N = 57)

From: High dose chemoradiotherapy increases chance of organ preservation with satisfactory functional outcome for rectal cancer

Variables Multivariate analysis
HR (95% CI) p value
Age (< 60 vs. ≥ 60) 3.618 (0.543–24.082) 0.184
Gender (male vs. female) 4.367 (0.503–37.888) 0.181
AJCC/UICC stage   
 I Reference 0.543
 II 0.176 (0.008–3.856) 0.270
 III 0.384 (0.029–5.118) 0.469
Courses of radiotherapy (one course vs. two course) 0.366 (0.016–8.127) 0.525
Cycles of chemotherapy (≤ 4 vs. > 4) 3.246 (0.148–71.163) 0.455
Response to treatment (cCR vs. non-cCR) 16.616 (1.883–146.634) 0.011*
  1. CSS cancer specific survival, HR hazard ratio, AJCC/UICC American Joint Committee on Cancer/International Union Against Cancer, cCR clinical complete response
  2. *Statistically significant