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Table 4 Multivariate analysis of the risk factors for CSS (N = 57)

From: High dose chemoradiotherapy increases chance of organ preservation with satisfactory functional outcome for rectal cancer

Variables

Multivariate analysis

HR (95% CI)

p value

Age (< 60 vs. ≥ 60)

3.618 (0.543–24.082)

0.184

Gender (male vs. female)

4.367 (0.503–37.888)

0.181

AJCC/UICC stage

  

 I

Reference

0.543

 II

0.176 (0.008–3.856)

0.270

 III

0.384 (0.029–5.118)

0.469

Courses of radiotherapy (one course vs. two course)

0.366 (0.016–8.127)

0.525

Cycles of chemotherapy (≤ 4 vs. > 4)

3.246 (0.148–71.163)

0.455

Response to treatment (cCR vs. non-cCR)

16.616 (1.883–146.634)

0.011*

  1. CSS cancer specific survival, HR hazard ratio, AJCC/UICC American Joint Committee on Cancer/International Union Against Cancer, cCR clinical complete response
  2. *Statistically significant