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Table 3 Chi square analysis for pre-RT and post-RT NLR

From: Association of neutrophil-to-lymphocyte ratio, radiotherapy fractionation/technique, and risk of development of distant metastasis among patients with locally advanced rectal cancer

  Pre-RT NLR Post-RT NLR
p value < 4.0 ≥ 4.0 p value < 4.0 ≥ 4.0
Sex
 Male 0.234 758 (90.9) 76 (9.1) 0.024 502 (57.0) 378 (43.0)
 Female 417 (92.3) 35 (7.7) 298 (62.7) 177 (37.3)
icT
 T1/2 0.557 107 (91.5) 10 (8.5) 0.024 88 (67.2) 43 (32.8)
 T3/4 1056 (91.3) 101 (8.7) 101 (57.9) 510 (42.1)
icN
 N0 0.453 211 (90.9) 21 (9.1) 0.307 155 (61.5) 97 (38.5)
 N1/2 915 (91.4) 86 (8.6) 605 (57.5) 444 (42.3)
RT modality
 3D-CRT 0.48 732 (91.3) 70 (8.7) < 0.001 532 (62.5) 319 (37.5)
 Tomotherapy 443 (91.5) 41 (8.5) 268 (53.2) 236 (46.8)
ypT
 T1/2 0.004 599 (93.6) 42 (6.4) < 0.001 427 (63.9) 241 (36.1)
 T3/4 573 (89.3) 69 (10.7) 371 (54.3) 312 (45.7)
ypN
 N0 0.386 855 (91.5) 79 (8.5) 0.15 574 (58.5) 407 (41.5)
 N1/2 318 (90.9) 32 (9.1) 224 (60.2) 148 (39.8)
Adjuvant chemotherapy
 No 0.389 539 (91.0) 53 (9.0) 0.001 343 (54.6) 285 (45.4)
 Yes 636 (91.6) 58 (8.4) 457 (62.9) 270 (37.1)
RT fractionation
 LCRT 0.513 1147 (91.3) 109 (8.7) 0.012 776 (58.6) 549 (41.4)
 SCRT 28 (93.3) 2 (6.7) 24 (80.0) 6 (20.0)
  1. 3D-CRT three-dimensional conformal radiotherapy, LCRT long-course RT, SCRT short-course RT