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Table 1 Patient and tumor characteristics for all 93 patients

From: The prognostic significance of pretreatment squamous cell carcinoma antigen levels in cervical cancer patients treated by concurrent chemoradiation therapy and a comparison of dosimetric outcomes and clinical toxicities between tomotherapy and volumetric modulated arc therapy

Characteristics

3DCRT (n = 9)

VMAT (n = 43)

Tomotherapy (n = 41)

P value

Age in years, median (range)

48 (34–66)

62 (38–84)

63 (34–89)

0.01

Age (years)

 < 60

8

20

17

0.034

 ≥ 60

1

23

24

 

OTT of RT (days)

 ≤ 61

6

21

13

0.091

 > 61

3

22

28

 

FIGO stage

 I

1

10

3

0.081

 II

4

25

22

 

 III

1

4

11

 

 IV

3

4

5

 

T classification

 T1/T2

6

35

25

0.114

 T3/T4

3

8

16

 

Nodal classification

 N0

2

32

25

0.011

 N1

7

11

16

 

Histological type

 Squamous cell carcinoma

8

40

39

0.607

 Adenocarcinoma

1

3

1

 

 Others

0

0

1

 

Mean EBRT dose (Gy)

55.1

54.1

54.2

0.516

Mean EQD2 of brachytherapy (Gy)

28.1

29.9

29.8

0.696

EQD2 of Point A (Gy)

 < 81

8

27

32

0.147

 ≥ 81

1

16

9

 

Pretreatment SCC Ag (ng/mL)

 ≤ 10

4

23

24

0.722

 > 10

5

20

17

 

Post-treatment SCC Ag (ng/mL)

 ≤ 1.5

8

38

32

0.399

 > 1.5

1

5

9

 

Median follow-up (months)

43

54

52

0.123

  1. 3DCRT three-dimensional conformal radiation therapy, VMAT volumetric modulated arc therapy, OTT overall treatment time, RT radiation therapy, FIGO the international federation of gynaecology and obstetrics, EBRT external beam radiation therapy, EQD2 equivalent dose in 2-Gy fractions, SCC Ag squamous cell carcinoma antigen