Table 3 Summary of genetic alterations in radiation-induced gliomas
Case no. | Secondary disease | IDH1/2 | BRAF | H3F3A | TERT | MGMT |
|---|---|---|---|---|---|---|
3 | GBM, IDH1/2 Wild-type | WT | ND | ND | WT | Hypomethylation |
4 | GBM, IDH1/2 Wild-type | WT | WT | WT | WT | Hypomethylation |
5 | GBM, IDH1/2 Wild-type | WT | WT | WT | WT | Hypomethylation |
6 | AA, IDH1/2 Wild-type | WT | WT | WT | WT | Hypermethylation |
7 | GBM, IDH1/2 Wild-type | WT | WT | WT | WT | Hypomethylation |
9 | GBM, IDH1/2 Wild-type | WT | ND | ND | WT | Hypomethylation |
10 | GBM, IDH1/2 Wild-type | WT | WT | WT | WT | Hypomethylation |
11 | GBM, IDH1/2 Wild-type | WT | WT | WT | WT | Hypermethylation |