Assessment of therapeutic outcome and role of reirradiation in patients with radiation-induced glioma

Radiation Oncology

Table 1 Characteristics of patients with primary diseases

Case no.	Sex	Age at primary disease (years)	Primary disease	Location	Therapy		Chemotherapy	Latency (years)
Case no.	Sex	Age at primary disease (years)	Primary disease	Location	Radiation therapy	Radiation dose (Gy)	Chemotherapy	Latency (years)
1	M	15	Germinoma	Suprasellar	Local, Local^a	41, 60^a	Yes	30
2	M	25	Pituitary adenoma	Sellar	Local	60	No	20
3	M	1	Acute lymphoblastic lymphoma	Systemic	TB	18	Yes	9
4	M	20	Germinoma	Suprasellar	WB	50	Yes	13
5	F	12	Pilocytic astrocytoma	Hypothalamus	Local	54	No	22
6	F	9	Medulloblastoma	Cerebellum	CS	WB: 35.6, Local: 66, WS: 31.9	Yes	30
7	F	10	Medulloblastoma	Cerebellum	CS	WB: 40, Local: 60, WS: 30	Yes	13
8	M	2	Acute lymphoblastic lymphoma	Systemic	TB	12	Yes	15
9	F	15	Diffuse astrocytoma, IDH2-mutant	Left Frontal	Local	60	Yes	17
10	F	39	Metastatic brain tumor from Lung cancer	Multiple	Local, WB	CK: 22, WB: 30	Yes (TKI)	10
11	M	6	Medulloblastoma	Cerebellum	CS	WB: 23.4, Local: 55.8, WS: 23.4	Yes	22

M male, F female, IDH isocitrate dehydrogenase, TB total body, CS craniospinal, WB whole brain, WS whole spine, CK cyberknife, TKI tyrosine kinase inhibitor
^aThis patient received radiotherapy of 41 Gy in 23 fractions at 15-year-old and of 60 Gy in 34 fractions at 17-year-old

ISSN: 1748-717X