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Table 5 Changes in quality-of-life scores after proton therapy

From: Outcomes of proton therapy for non-small cell lung cancer in patients with interstitial pneumonia

Variable

Pre-PT

3 Months

P value

(N = 28)

(N = 22)

EORTC QLQ-C30

   

Global health status/QOL

50.9 (27.8)

49.6 (27.0)

0.95

Functional scales

   

Physical functioning

73.8 (21.9)

75.8 (17.8)

0.98

Role functioning

71.4 (27.5)

77.3 (19.6)

0.58

Emotional functioning

79.5 (19.3)

89.0 (13.0)

0.07

Cognitive functioning

74.4 (24.6)

78.0 (20.8)

0.72

Social functioning

80.9 (20.6)

89.4 (15.9)

0.12

Symptom scales/items

   

Fatigue

34.5 (24.8)

29.3 (17.7)

0.53

Nausea and vomiting

2.98 (9.13)

3.03 (11.1)

0.88

Pain

12.5 (20.6)

6.82 (11.1)

0.46

Dyspnea

35.7 (25.6)

45.4 (22.0)

0.19

Insomnia

17.9 (23.1)

18.2 (24.6)

0.98

Appetite loss

15.5 (26.4)

10.6 (23.9)

0.45

Constipation

19.1 (27.9)

19.7 (24.5)

0.75

Diarrhea

8.33 (17.3)

9.08 (15.2)

0.70

Financial difficulties

26.2 (33.2)

15.2 (24.6)

0.21

EORTC QLQ-LC13

   

Symptom scales/items

   

Dyspnea

27.4 (21.7)

31.8 (16.2)

0.32

Coughing

30.9 (22.1)

36.4 (30.7)

0.51

Hemoptysis

3.57 (10.5)

4.54 (11.7)

0.77

Sore mouth

4.76 (11.9)

3.03 (9.80)

0.59

Dysphagia

7.14 (21.0)

4.55 (15.6)

0.60

Peripheral neuropathy

8.33 (14.7)

12.1 (19.4)

0.55

Alopecia

13.1 (27.7)

3.03 (9.80)

0.14

Pain in chest

7.14 (16.6)

10.6 (15.9)

0.30

Pain in arm or shoulder

9.52 (20.0)

10.6 (18.9)

0.70

Pain in other parts

11.9 (14.7)

9.09 (18.3)

0.82

SF-36

   

Symptom scales/items

   

Physical functioning

66.4 (23.8)

68.0 (21.3)

1.00

Role-physical

57.8 (33.0)

65.1 (26.6)

0.40

Bodily pain

75.9 (27.5)

80.2 (19.8)

0.86

General health

48.6 (16.1)

50.5 (18.2)

0.35

Vitality

58.5 (25.2)

61.1 (22.6)

0.70

Social functioning

70.5 (29.7)

77.8 (20.4)

0.55

Role-emotional

64.3 (31.4)

70.5 (29.5)

0.50

Mental health

66.1 (22.0)

67.3 (19.4)

0.73

3-Physical CS*

40.6 (11.1)

41.3 (10.5)

0.95

3-Mental CS*

55.6 (10.2)

55.8 (8.29)

0.95

3-Role-social CS*

39.9 (15.1)

43.5 (10.9)

0.43

2-Physical CS*

35.3 (14.3)

38.4 (12.6)

0.54

2-Mental CS*

53.7 (10.7)

54.5 (8.54)

0.82

  1. *Scored using factor coefficients based on the 1995 Japan National Survey; CS component summary; Data are shown as mean (standard deviation) values