Table 4 Relationships between dose-volume-histogram parameters and the incidence of grade 2 or higher late radiation pneumonitis
From: Outcomes of proton therapy for non-small cell lung cancer in patients with interstitial pneumonia
|  | Grade ≤ 1 | Grade ≥ 2 | P value | ||
|---|---|---|---|---|---|
Pneumonitis (N = 25) | Pneumonitis (N = 4) | ||||
Median | IQR | Median | IQR | ||
Lung-GTV | Â | Â | Â | Â | Â |
MLD (GyRBE) | 7.0 | (3.4–11.2) | 10.8 | (8.2–12.9) | 0.36 |
V5GyRBE (%) | 21.8 | (11.1–28.0) | 26.7 | (19.0–32.7) | 0.44 |
V10GyRBE (%) | 18.6 | (8.8–25.7) | 24.7 | (17.7–29.9) | 0.44 |
V20GyRBE (%) | 13.7 | (6.4–19.6) | 20.2 | (15.1–24.3) | 0.37 |