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Table 1 The baseline characteristics of the eligible studies and included patients

From: Efficacy and safety of re-irradiation for locoregional esophageal squamous cell carcinoma recurrence after radiotherapy: a systematic review and meta-analysis

Study

Country

Study design

Sample size

Age (years)

Male (%)

Stage (I–II/III–IV)

Interval from prior therapy to irradiation

Total radiation dose

Study quality

Shioyama 2007 [19]

Japan

Retrospective

82

61.0

85.4

57/24

10.0 months

50.4 Gy

6

Nonoshita 2007 [20]

Japan

Retrospective

6

70.5

100.0

6/0

4.3 months

22.8 Gy

4

Maruyama 2011 [21]

Japan

Retrospective

28

64.2

92.9

12/16

NA

60 Gy

4

Kim 2012 [22]

Korea

Retrospective

10

72.5

90.0

6/4

15.6 months

46.5 Gy

5

Zhou 2015 [23]

China

Retrospective

55

66.8

49.1

54/1

NA

51.9 Gy

6

Katano 2017 [24]

Japan

Retrospective

6

60.8

100.0

NA

25.2 months

50.4 Gy

4

Hong 2018 [25]

China

Retrospective

87

62.0

74.7

23/47

16.0 months

60 Gy

5

Xu 2019 [26]

China

Retrospective

47

72.0

74.5

24/23

26.0 months

58 Gy

6

Zhao 2020 [27]

China

Retrospective

252

69.0

81.7

79/173

30.0 months

72 Gy

6