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Table 5 Prognostic factors

From: Chemoradiotherapy is an alternative choice for patients with primary mediastinal seminoma

Prognostic factor

10-year LRFS (%)

10-year DMFS (%)

10-year PFS (%)

Yes

No

p

Yes

No

p

Yes

No

p

Male

90.8

100

0.838

100

0.00

0.000

90.8

0.0

0.002

Age, < 18 years

75.0

95.2

0.251

100

94.1

0.628

75.0

85.3

0.943

Symptoms

89.5

100

0.569

94.4

100

0.683

84.2

100

0.801

SVCS

100

84.8

0.238

100

92.3

0.433

100

77.8

0.011

Alcohol use

90.8

100

0.838

95.2

100

86.3

100

0.838

Smoking

100

88.7

0.472

100

94.1

0.628

100

83.0

0.620

GVI

93.3

83.3

0.352

100

83.3

0.114

93.3

66.7

0.307

Diameter, > 10 cm

100

83.6

0.194

90.0

100

0.294

90.0

83.6

0.407

LNM

100

88.1

0.419

80.0

100

0.704

80.0

88.1

0.602

DMPD

100

90.3

0.706

50.0

100

0.002

50.0

90.3

0.097

Masaoka stage III–IV

90.0

100

0.651

94.7

100

0.746

87.0

100

0.574

R0 resection

100

86.3

0.305

87.5

100

0.202

87.5

86.3

0.715

Radiotherapy

93.3

87.5

0.797

92.3

100

0.433

85.6

87.5

0.236

Chemotherapy

90.5

100

0.755

95.0

100

0.823

100

85.7

0.188

  1. DMFS distant metastasis-free survival, DMPD distant metastasis at the primary diagnosis, GVI great vessel invasion, LNM lymph node metastasis, LRFS local–regional relapse-free survival, PFS progression-free survival, SVCS superior vena cava syndrome