Table 1 Patients’ characteristics
From: Chemoradiotherapy is an alternative choice for patients with primary mediastinal seminoma
Characteristic | All N (%) | NS N (%) | S N (%) | p | Characteristic | All N (%) | NS N (%) | S N (%) | p |
|---|---|---|---|---|---|---|---|---|---|
Sex | 0.290 | Primary tumor invasive site | |||||||
Male | 26 (96.3) | 14 (100) | 12 (92.3) | 1R | 5 (18.5) | 4 (28.6) | 1 (7.7) | 0.163 | |
Female | 1 (3.7) | 0 (0) | 1 (7.7) | 1L | 5 (18.5) | 4 (28.6) | 1 (7.7) | 0.163 | |
Age, years | 0.918 | 2R | 11 (40.7) | 9 (64.3) | 2 (15.4) | 0.010 | |||
≤ 18 | 7 (25.9) | 3 (21.4) | 3 (23.1) | 2L | 11 (40.7) | 6 (42.9) | 5 (38.5) | 0.816 | |
> 18 | 20 (74.1) | 11 (78.6) | 10 (76.9) | 3A | 27 (100.0) | 14 (100) | 13 (100) | 1.000 | |
First symptom | 0.200 | 3P | 6 (22.2) | 5 (35.7) | 1 (7.7) | 0.080 | |||
Dyspnea | 6 (22.2) | 2 (14.3) | 4 (30.8) | 4R | 11 (40.7) | 9 (64.3) | 2 (15.4) | 0.010 | |
Chest pain | 8 (29.6) | 5 (35.7) | 3 (23.1) | 4L | 11 (40.7) | 6 (42.9) | 5 (38.5) | 0.816 | |
Cough | 7 (25.9) | 4 (28.6) | 3 (23.1) | 5 | 14 (51.9) | 8 (57.1) | 6 (46.2) | 0.568 | |
Vomit | 1 (3.7) | 1 (7.1) | 0 (0) | 6 | 19 (70.4) | 11 (78.6) | 8 (61.5) | 0.333 | |
Facial edema | 2 (7.4) | 2 (14.3) | 0 (0) | 7 | 4 (14.8) | 3 (21.4) | 1 (7.7) | 0.315 | |
Symptomless | 3 (11.1) | 0 | 3 (23.1) | 8 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1.000 | |
SVCS | 0.148 | 9R | 1 (3.7) | 1 (7.1) | 0 (0.0) | 0.326 | |||
Yes | 10 (37.0) | 7 (50.0) | 3 (23.1) | 9L | 2 (7.4) | 0 (0.0) | 2 (15.4) | 0.127 | |
No | 17 (63.0) | 7 (50.0) | 10 (76.9) | 10R | 1 (3.7) | 1 (7.1) | 0 (0.0) | 0.326 | |
ECOG PS score | 0.056 | 10L | 4 (14.8) | 1 (7.1) | 3 (23.1) | 0.244 | |||
0 | 3 (11.1) | 0 (0) | 3 (23.1) | PDL | 2 (7.4) | 2 (14.3) | 0 (0.0) | 0.157 | |
1 | 24 (88.9) | 14 (100) | 10 (76.9) | Invaded adjacent tissue | |||||
Alcohol use | 0.557 | Aorta | 15 (55.6) | 11 (78.6) | 4 (30.8) | 0.013 | |||
Yes | 1 (3.7) | 0 (0) | 1 (7.7) | PA | 8 (29.6) | 4 (28.6) | 4 (30.8) | 0.901 | |
No | 26 (96.3) | 14 (100) | 12 (92.3) | SVC | 15 (55.6) | 12 (85.7) | 3 (23.1) | 0.001 | |
Smoking | 0.557 | PV | 3 (11.1) | 1 (7.1) | 2 (15.4) | 0.496 | |||
Yes | 5 (19.5) | 2 (14.3) | 3 (23.1) | BV | 5 (18.5) | 2 (14.3) | 3 (23.1) | 0.557 | |
No | 22 (81.5) | 12 (85.7) | 10 (76.9) | AV | 1 (3.7) | 1 (7.1) | 0 (0.0) | 0.326 | |
Maximum diameter, cm | 0.228 | CA | 2 (7.4) | 1 (7.1) | 1 (7.7) | 0.957 | |||
≤ 5 | 2 (7.4) | 0 (0) | 2 (15.4) | CV | 1 (3.7) | 0 (0.0) | 1 (7.7) | 0.290 | |
5.1–10 | 14 (51.9) | 7 (50.0) | 7 (53.8) | Lung | 12 (44.4) | 6 (42.9) | 6 (46.2) | 0.863 | |
> 10 | 11 (40.7) | 7 (50.0) | 4 (30.8) | Pericardium | 13 (48.1) | 7 (50.0) | 6 (46.2) | 0.842 | |
Adjacent tissue invasion | 0.056 | Heart | 2 (7.4) | 1 (7.1) | 1 (7.7) | 0.957 | |||
Yes | 24 (88.9) | 14 (100) | 10 (76.9) | Bronchus | 1 (3.7) | 0 (0.0) | 1 (7.7) | 0.290 | |
No | 3 (11.1) | 0 (0) | 3 (23.1) | Trachea | 1 (3.7) | 0 (0.0) | 1 (7.7) | 0.290 | |
Great vessel invasion | 0.001 | Sternum | 2 (7.4) | 2 (14.3) | 0 (0.0) | 0.157 | |||
Yes | 20 (74.1) | 14 (100) | 6 (46.2) | Masaoka stage | 0.028 | ||||
No | 7 (25.9) | 0 (0) | 7 (53.8) | I | 2 (7.4) | 0 (0.0) | 2 (15.4) | ||
Lymph node metastasis | 0.745 | II | 1 (3.7) | 0 (0.0) | 1 (7.7) | ||||
Yes | 7 (25.9) | 4 (28.6) | 3 (23.1) | IIIa | 4 (14.8) | 0 (0.0) | 4 (30.8) | ||
No | 20 (74.1) | 10 (71.4) | 10 (76.9) | IIIb | 13 (48.1) | 10 (71.4) | 3 (23.1) | ||
Distant metastasis | 0.957 | IVa | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||||
Yes | 2 (7.4) | 1 (7.1) | 1 (7.7) | IVb | 7 (25.9) | 4 (28.6) | 3 (23.1) | ||
No | 25 (92.6) | 13 (92.9) | 12 (92.3) |