Variability of α/β ratios for prostate cancer with the fractionation schedule: caution against using the linear-quadratic model for hypofractionated radiotherapy

Table 3 Moderately hypofractionated radiotherapy group

Study number	Author	Number of patients	5y-bRFS	Total dose (D)	Fractions (N)	D²/N (C)	Definition of bRFS^b
1	Arcangeli	83	0.85	62	20	192.2	P
2	Catton	608	0.85	60	20	180	P
3	Cheung	230	0.837	67.5	25	182.25	P
4	Chin,S	112	0.68	52.5	20	137.8125	P
5	Dearnaley	1077	0.859	57	19	171	P
5	Dearnaley	1074	0.906	60	20	180	P
6	Di Muzio	80	0.911	74.2	28	196.63	P
	Di Muzio	78	0.946	71.4	28	182.07	P
	Di Muzio	53	0.962	74.2	28	196.63	P
7	Faria	82	0.954	66	22	198	P
8	Fonteyne	113	0.94	56	16	196	P
9	Hashimoto	195	0.924	66	22	198	P
10	Lieng	96	0.81	60	20	180	P
10	Lieng	27	0.88	66	22	198	P
11	Incrocci	407	0.805	64.6	19	219.64	P
12	Kim	30	0.929	70	28	175	P
13	Kuban	102	0.96	72	30	172.8	A
14	Kupelian	100	0.88	70	28	175	P
15	Kupelian	770	0.83	70	28	175	P
16	Leborgne	114	0.894	61.2	20	187.272	P
17	Mai	596	0.927	76.65	35	167.8635	P
18	Patel	129	0.97	66	22	198	P
19	Pervez	60	0.9167	67.5	25	182.25	P
20	Pollack	151	0.81	70.2	26	189.54	P
21	Shimizu	73	0.77	74.8	34	164.56	P
	Shimizu	21	0.92	74.8	34	164.56	P
	Shimizu	44	0.95	72.6	33	159.72	P
22	Thomson	30	0.5	57	19	171	P
22	Thomson	30	0.58	60	20	180	P
23	Viani	149	0.946	69	23	207	P
24	Yeoh	108	0.574	55	20	151.25	A

ISSN: 1748-717X