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Table 2 Repeated measures ANOVA for the quantitative parameters compared by the imaging method

From: Response assessment after stereotactic body radiation therapy for spine and non-spine bone metastases: results from a single institutional study

 

CT contrast enhanced

MRI

PET/CT

Total

RM ANOVA effects

M

SD

n

M

SD

n

M

SD

n

M

SD

n

SBRT

Imaging

Width

              

Pre-SBRT

21.09

11.73

15

20.58

12.74

26

21.91

14.45

14

21.91

14.45

55

F = 2.55 (p = 0.116) η2 = 0.05

F = 6.13 (p = 0.004)*

η2 = 0.19

Post-SBRT

29.33

15.27

15

21.40

14.31

26

18.84

8.13

14

18.84

8.13

55

  

Depth

              

Pre-SBRT

20.46

10.26

15

24.03

13.81

26

22.67

14.65

14

22.71

13.02

55

F = 3.97 (p = 0.052) η2 = 0.07

F = 3.12 (p = 0.053) η2 = 0.11

Post-SBRT

25.68

10.99

15

24.76

15.72

26

22.25

11.03

14

24.37

13.30

55

  

Height

              

Pre-SBRT

17.09

6.07

15

17.66

8.28

26

22.27

17.85

14

18.68

11.07

55

F = 0.15 (p = 0.701) η2 = 0.003

F = 3.05 (p = 0.056) η2 = 0.11

Post-SBRT

20.94

5.05

15

18.55

7.85

26

18.83

7.64

14

19.27

7.09

55

  

Volume

              

Pre-SBRT

9997.74

13,068.83

16

12,775.66

15,571.32

26

29,478.44

74,682.81

14

16,157.66

39,201.12

56

F = 0.42 (p = 0.502) η2 = 0.01

F = 2.23 (p = 0.118) η2 = 0.08

Post-SBRT

17,678.62

19,147.79

16

14,338.71

17,120.47

26

10,532.05

9453.02

14

14,341.30

16,164.13

56

  

CT-DN

              

Pre-SBRT

248.57

307.38

7

300.64

259.62

14

283.29

269.80

21

F = 2.05 (p = 0.168) η2 = 0.10

F = 0.08 (p = 0.778) η2 = 0.01

Post-SBRT

300.14

324.13

7

377.93

337.06

14

352.00

326.76

21

  

CT-CE

              

Pre-SBRT

263.71

323.85

7

         

 

Post-SBRT

263.71

323.85

7

           

T2-SI

              

Pre-SBRT

224.71

175.53

19

F = 0.01 (p = 0.947) η2 = 0.00

 

Post-SBRT

222.74

206.11

19

  

T2-TSI

              

Pre-SBRT

214.82

194.65

8

F = 0.06 (p = 0.816) η2 = 0.01

 

Post-SBRT

225.63

163.17

8

  

T1-NSI

              

Pre-SBRT

213.76

141.40

21

F = 0.01 (p = 0.945) η2 = 0.00

 

Post-SBRT

215.69

171.15

21

  

T1-CESI

              

Pre-SBRT

   

417.03

284.76

20

F = 0.01 (p = 0.945) η2 = 0.00

 

Post-SBRT

   

357.85

267.84

20

  
  1. p < 0.1 is considered as significant
  2. η2 = 0.01 weak, η2 = 0.06 moderate, η2 = 0.14 high effect, according to Cohen, J (1988). Statistical power analysis for the behavioral sciences (2nd ed.). Hillsdale, NJ: Erlbaum
  3. CT, computed tomography; MRI, magnetic resonance imaging; PET/CT, positron emission tomography/ computed tomography; RM, repeated measures; M, mean; SD, standard deviation; SBRT, stereotactic body radiotherapy; CT-DN, computed tomography density native in Hounsfield units; CT-CE, computed tomography density contrast enhanced in Hounsfield units; T2-SI, T2-weighted images signal intensity; T2-TSI, T2-weighted images turbo inversion recovery magnitude signal intensity; T1-NSI, T1-weighted images native signal intensity; T1-CESI, T1-weighted images contrast enhanced signal intensity
  4. *Statistically significant; p < 0.10