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Table 3 Dose intensity based on the dose volume histogram for tumor location

From: Factors associated with long-term survival in gemcitabine-concurrent proton radiotherapy for non-metastatic locally advanced pancreatic cancer: a single-center retrospective study

 

Head

Body-tail

 

Parameter

Median value (range)

Median value (range)

P value

GTV

   

 Volume, cc

39.2 (7.9–88.9)

49.2 (9.1–141.0)

0.038

 V60GyE, %

50.0 (6.2–98.7)

66.8 (25.2–99.7)

 < 0.001

 Dmax, GyE

68.7 (66.8–72.0)

68.8 (66.8–71.1)

0.406

 Dmean, GyE

58.8 (48.8–66.4)

61.4 (50.7–67.3)

 < 0.001

 Dmin, GyE

45.0 (40.0–55.6)

45.2 (36.5–58.3)

0.752

CTV

   

 Volume, cc

175.5 (89.7–417.0)

196.3 (85.0–420.6)

0.434

 V60GyE, %

58.7 (25.6–82.7)

61.2 (37.7–86.7)

0.223

 Dmax, GyE

69.7 (67.7–72.7)

69.7 (68.0–71.7)

0.285

 Dmean, GyE

60.3 (52.1–64.7)

60.6 (54.8–65.5)

0.207

 Dmin, GyE

44.3 (31.6–47.6)

44.4 (38.2–50.2)

0.697

PTV

   

 Volume, cc

340.1 (184.3–728.6)

364.3 (175.7–696.5)

0.535

 V60GyE, %

47.9 (20.3–69.1)

48.4 (27.4–75.3)

0.335

 Dmax, GyE

69.9 (67.7–72.7)

69.8 (68.0–72.2)

0.192

 Dmean, GyE

57.6 (48.8–62.3)

57.7 (52.3–63.4)

0.222

 Dmin, GyE

37.2 (23.0–41.4)

37.4 (28.5–45.1)

0.208

  1. GTV gross tumor volume; CTV clinical target volume; PTV planning target volume; GyE Gy equivalents; V60GyE the volume ratio irradiated over 60 GyE; Dmax the maximum dose of the target volume; Dmean the average dose of the target volume; Dmin the minimum dose of the target volume
  2. Significant P values (< 0.05) are in bold