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Table 1 Demographics of patients with breast cancer and heart failure with reduced ejection fraction who received total mastectomy in the propensity score–weighted population through inverse probability of treatment weighting

From: Adjuvant postmastectomy radiotherapy might be associated with better survival in women with heart failure receiving total mastectomy

 

Propensity score weighting population

Adjuvant RT

N = 143

Non-RT

N = 503

Standardized difference

n

(%)

n

(%)

Age

 Mean (SD)

67.5

(11.3)

67.7

(11.2)

0.0215

 Median (Q1–Q3)

67

(57–72)

67

(61–77)

 

 20–69

67

(46.9)

238

(47.9)

0.0096

 70+

76

(53.1)

259

(52.1)

 

Diagnosis year

 2009–2012

88

(50.9)

250

(50.3)

0.0115

 2013–2016

85

(49.1)

247

(49.7)

 

CCI scores

 0

44

(30.8)

123

(24.5)

0.1433

 1+

99

(69.2)

380

(75.5)

 

Differentiation

 I

20

(14.0)

72

(14.3)

0.0212

 II

77

(53.8)

273

(54.3)

0.0311

 III

46

(32.1)

158

(31.4)

0.0207

AJCC pathologic stage

 II

17

(12.8)

61

(12.1)

0.0114

 IIIA

68

(47.6)

241

(47.9)

0.0162

 IIIB–C

58

(40.6)

201

(40.0)

0.0142

pT

 pT1

9

(6.3)

30

(5.9)

0.0238

 pT2

58

(40.6)

202

(40.2)

0.0149

 pT3–4

76

(53.1)

271

(53.9)

0.0130

pN

 pN0

57

(39.8)

200

(39.8)

0.0000

 pN1

43

(30.1)

151

(30.0)

0.0013

 pN2–3

43

(30.1)

152

(30.2)

0.0001

Hypertension

110

(76.9)

387

(76.9)

0.0001

CAD

53

(37.1)

184

(36.6)

0.0092

Diabetes

60

(42.0)

215

(42.7)

0.0097

Anthracycline-based chemotherapy

76

(53.1)

260

(51.7)

0.0280

Hormone receptor positive

59

(41.3)

229

(45.5)

0.0934

Trastuzumab use

69

(48.3)

246

(48.9)

0.0031

Nodal surgery

 ALND

87

(60.8)

302

(60.0)

0.0079

 SLNB

56

(39.2)

201

(40.0)

 

Hospital level

 Academic center

80

(55.9)

285

(56.7)

0.0181

 Nonacademic center

63

(44.1)

218

(43.3)

 
  1. RT radiotherapy, IQR interquartile range, SD standard deviation, AJCC American Joint Committee on Cancer, HER2 human epidermal growth factor receptor-2, CCI Charlson comorbidity index, T tumor, N nodal, pT pathologic tumor stage, pN pathologic nodal stage, ALND axillary lymph node dissection, SNLB sentinel lymph node biopsy, CAD coronary arterial disease