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Table 3 Comparisons between the anticoagulant and non-anticoagulant groups

From: Patient-related risk factors for late rectal bleeding after hypofractionated radiotherapy for localized prostate cancer: a single-center retrospective study

Variables

Non-AC (%)

AC (%)

Before IPTW

After IPTW

P value

P value

Age (years)

  

0.004

0.891

  < 74

78 (51.7)

30 (37.5)

  

 ≥ 74

73 (48.3)

50 (62.5)

  

Risk category

  

0.106

0.947

 Very low–low

9 (6.0)

7 (8.8)

  

 Intermediate

26 (17.2)

22 (27.5)

  

 High–very high

116 (76.8)

51 (63.7)

  

Gleason score

  

0.211

0.987

 2–6

18 (11.9)

15 (18.8)

  

 7

67 (44.4)

38 (47.5)

  

 8–10

66 (43.7)

27 (33.8)

  

Initial PSA concentration (μg/L)

  

0.138

0.802

  < 10

51 (33.8)

37 (46.2)

  

 10–20

50 (33.1)

24 (30.0)

  

  ≥ 20

50 (33.1)

19 (23.8)

  

T stage

  

0.085

0.613

 T1–2

47 (31.1)

34 (42.5)

  

  ≥ T3

104 (68.9)

46 (57.5)

  

Diabetes

  

0.001

0.883

 No

130 (86.1)

54 (67.5)

  

 Yes

21 (13.9)

26 (32.5)

  

Hypertension

  

 < 0.001

0.782

 No

88 (58.3)

26 (32.5)

  

 Yes

63 (41.7)

54 (67.5)

  

Cirrhosis

  

0.560

0.698

 No

145 (96.0)

78 (97.5)

  

 Yes

6 (3.97)

2 (2.50)

  

Whole-pelvic radiotherapy

  

0.202

0.575

 No

101 (66.9)

60 (75.0)

  

 Yes

50 (33.1)

20 (25.0)

  

Androgen-deprivation therapy

  

0.231

0.973

 No

31 (20.5)

22 (27.5)

  

 Yes

120 (79.5)

58 (72.5)

  

Radiation dose

  

0.462

0.788

 67.2 Gy

53 (35.1)

32 (40.0)

  

 70 Gy

98 (64.9)

48 (60.0)

  

IMRT technique

  

0.360

0.893

 Static

44 (29.1)

28 (35.0)

  

 Arc

107 (70.9)

52 (65.0)

  
  1. AC, anticoagulant; IMRT, intensity-modulated radiation therapy; IPTW, inverse probability of treatment weighting; PSA, prostate-specific antigen