Table 3 Lists plan evaluation parameters and %difference/statistical results for GTV, PTV65 and PTV54 across all three groups
Parameters | Group I (65 Gy) | Group II (73 Gy) | Group III (82 Gy) | I vs II | I vs III |
|---|---|---|---|---|---|
Dose-volume values (Gy) | Mean ± SD (95% CI) | Mean ± SD (95% CI) | Mean ± SD (95% CI) | % Diff (p-value) | % Diff (p-value) |
Targets | |||||
GTV (D98%) | 64.0 ± 0.4 (63.8–64.2) | 71.9 ± 0.4 (71.7–72.0) | 80.0 ± 0.8 (79.6–80.3) | + 12.3% (p < 0.02) | + 25.0% (p < 0.02) |
GTV (D50%) | 65.6 ± 0.5 (65.4–65.8) | 73.8 ± 0.3 (73.7–73.9) | 82.6 ± 0.2 (82.5–82.7) | + 12.5% (p < 0.02) | + 25.9% (p < 0.02) |
GTV (D2%) | 67.5 ± 0.5 (67.3–67.8) | 74.8 ± 0.2 (74.7–74.9) | 83.8 ± 0.4 (83.6–83.9) | + 10.8% (p < 0.02) | + 24.1% (p < 0.02) |
PTV65 (D98%) | 62.8 ± 0.4 (62.6–62.9) | 62.6 ± 0.3 (62.5–62.7) | 62.2 ± 1.2 (61.6–62.8) | − 0.3% (p = 0.19) | − 1.0% (p < 0.02) |
PTV65 (D50%) | 65.8 ± 0.2 (65.7–65.8) | 65.7 ± 0.2 (65.6–65.8) | 65.6 ± 0.2 (65.5–65.7) | − 0.3% (p = 0.28) | − 0.3% (p < 0.02) |
PTV65 (D2%) | 68.5 ± 0.4 (68.3–68.7) | 73.6 ± 0.9 (73.2–74.0) | 82.4 ± 1.1 (81.9–82.9) | + 7.4% (p < 0.02) | + 20.3% (p < 0.02) |
PTV54 (D98%) | 51.5 ± 0.4 (51.3–51.7) | 51.8 ± 0.3 (51.7–52.0) | 52.0 ± 0.5 (51.8–52.3) | + 0.6% (p < 0.02) | + 1.0% (p < 0.02) |
PTV54 (D50%) | 54.9 ± 0.5 (54.7–55.1) | 55.2 ± 0.5 (55.0–55.5) | 55.4 ± 0.6 (55.2–55.8) | + 0.5% (p = 0.05) | + 1.0% (p < 0.02) |
PTV54 (D2%) | 60.4 ± 0.8 (60.1–60.8) | 60.4 ± 0.7 (60.0–60.7) | 60.5 ± 0.7 (60.2–60.8) | 0.0% (p = 0.81) | + 0.1% (p = 0.80) |