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Table 1 Dose-volume planning objectives for target volumes and organs at risk

From: Adaptive dose escalated radiotherapy in oropharyngeal cancers: a treatment planning feasibility study

Structure

Dose-volume planning objective

PTV65 (65 Gy prescribed in 30 fractions);

99% volume more than 90% of the dose (D99% > 90%)

98% volume more than 95% of the dose (D98% > 95%)

50% volume equal to 100% of the dose (D50% = 100%)

5% volume less than 105% of the dose (D5% < 105%)

2% volume less than 107% of the dose (D2% < 107%)

PTV54 (54 Gy prescribed in 30 fractions);

99% volume more than 90% of the dose (D99% > 90%)

98% volume more than 95% of the dose (D98% > 95%)

50% volume equal to 100% of the dose (D50% = 100%)

5% volume less than 117% of the dose (D5% < 117%)

2% volume less than 122% of the dose (D5% < 122%)

PRV Spinal Cord

1% of volume less than 44 Gy; (D1% < 44 Gy)

Dmax less than 48 Gy

PRV Brainstem

1% of volume less than 48 Gy (D1% < 48 Gy)

Ipsi-lateral Parotid

As low as reasonably practicable

Contra-lateral Parotid

Dmean less than 24 Gy

Larynx

Dmean less than 40 Gy

  1. GTV; dose-volume planning objectives similar to as described for PTV65 but for an overall escalated prescribed dose of 73 Gy in 30 fractions or 82 Gy in 30 fractions