Skip to main content
Fig. 2 | Radiation Oncology

Fig. 2

From: Molecular features of glioblastomas in long-term survivors compared to short-term survivors—a matched-pair analysis

Fig. 2

This figure shows the OS in the overall population (LTS, STS-1, STS-2) by MGMT and GFAP status; the black curve represents patients which are positive for GFAP and also have a hypermethylated MGMT promoter region. The blue curve represents patients with mixed expression; i.e., either a hypermethylated MGMT promoter region combined with an at least partially negative GFAP expression in the tumor and vice versa. The red curve shows OS outcomes for patients who had an at least partially negative GFAP staining in the tumor and who had an unmethylated MGMT promoter region. Differences between the double-positive patients compared to mixed patients was significant (p = 0.01) and the difference between mixed patients and double-negative patients was also significant (p = 0.038)

Back to article page