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Table 2 Univariate and multivariate analysis of relationship between treatment strategies and INN occurrence

From: Irradiation-induced nasopharyngeal necrosis (INN) in newly diagnosed nasopharyngeal carcinoma treated by intensity-modulated radiation therapy: clinical characteristics and the influence of treatment strategies

Variables Univariate Multivariate
OR (95% IC) value OR (95% IC) value
No chemotherapy 1.092 (0.568–2.099) 0.792 3.035 (0.398–23.162) 0.284
AC 2.082 (0.602–7.194) 0.247 2.099 (0.530–8.315) 0.291
NC 0.632 (0.233–1.716) 0.368 0.554 (0.171–1.790) 0.324
CC 0.940 (0.501–1.763) 0.847 0.387 (0.057–2.605) 0.329
Target therapy 0.647 (0.320–1.312) 0.227 0.536 (0.252–1.141) 0.106
Local boost 7.360 (2.301–23.547) 0.001 7.768 (2.340–25.785) 0.001
Chemotherapy strategies (NC + CCRT, CCRT + AC, CCRT) 0.475
  1. AC adjuvant chemotherapy, NC neoadjuvant chemotherapy, CC Concurrent chemotherapy, RT radiotherapy