Prognostic value of tumor measurement parameters and SCC-Ag changes in patients with locally-advanced cervical cancer

Table 2 Univariate analysis of OS and PFS

Variable	Univariate analysis
Variable	5-y OS (%)	P	5-y PFS (%)	P
Age (years)
< 54	65.7	0.201	59.3	0.118
≥ 54	73.7	0.201	70.5	0.118
FIGO stage
≤ IIb	78.2	0.001	73.1	0.002
> IIb	57.1	0.001	52.4	0.002
Infection
Yes	33.3	< 0.001	33.3	0.001
No	72.3	< 0.001	67.0	0.001
Anemia
Yes	56.2	< 0.001	50.0	< 0.001
No	78.0	< 0.001	74.0	< 0.001
Lymph node metastasis
Yes	56.1	0.012	47.4	< 0.001
No	74.7	0.012	71.2	< 0.001
TD_pre* (cm)
≤ 4.4	84.1	< 0.001	80.7	< 0.001
> 4.4	58.3	< 0.001	52.2	< 0.001
TV_pre* (cm³)
≤ 45.71	81.9	< 0.001	78.1	< 0.001
> 45.71	56.1	< 0.001	50.0	< 0.001
TD_post* (cm)
≤ 2.4	84.3	< 0.001	79.5	< 0.001
> 2.4	44.7	< 0.001	39.5	< 0.001
TV_post* (cm³)
≤ 10.45	82.5	< 0.001	78.1	< 0.001
> 10.45	42.4	< 0.001	36.4	< 0.001
TVRR* (%)
< 80.1	46.2	< 0.001	41.0	< 0.001
≥ 80.1	84.0	< 0.001	79.2	< 0.001
Radiotherapy
IMRT	72.4	0.371	64.2	0.928
CRT	65.0	0.371	65.0	0.928
Total dose of radiotherapy (Gy)
≤ 84	71.0	0.783	62.6	0.497
> 84	67.7	0.783	66.7	0.497
Number of chemotherapy cycles
< 4	55.4	0.004	52.3	0.026
≥ 4	76.1	0.004	70.3	0.026
SCC_pre (µg/L)
≤ 11.4	75.2	0.001	73.1	< 0.001
> 11.4	55.2	0.001	43.1	< 0.001
SCC_post (µg/L)
≤ 1.9	75.3	< 0.001	70.6	< 0.001
> 1.9	34.5	< 0.001	17.4	< 0.001
SCCRR (%)
= 100	75.4	< 0.001	69.7	< 0.001
< 100	33.3	< 0.001	20.8	< 0.001

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