Endoscopic resection as an independent predictive factor of local control in patients with T1bN0M0 esophageal squamous cell carcinoma treated with chemoradiotherapy: a retrospective study

Table 4 Univariate analyses for disease-specific survival and local recurrence-free survival rates

Variables	Number	5-year DSS (%)	p value	5-year LRFS (%)	p value
Age, years
< 70	43	92.9	0.059	91.8	0.140
≥ 70	48	74.5		82.8
Gender
Male	77	81.3	0.094	89.3	0.899
Female	14	100.0		78.8
Performance status
0	86	87.3	0.001*	87.0	0.498
≥ 1	5	40.0		100.0
Tumor location
Upper thoracic	10	75.0	0.829	77.1	0.567
Middle thoracic	54	85.5		90.9
Lower thoracic	27	87.4		90.9
Tumor length
< 3 cm	46	91.9	0.111	97.4	0.012*
≥ 3 cm	45	76.3		76.7
Circumference of tumor
< 3/4	73	85.5	0.681	89.6	0.131
≥ 3/4	18	80.1		79.1
Multiple lesion
No	77	85.2	0.757	87.2	0.824
Yes	14	79.6		92.3
Endoscopic resection
No	28	72.1	0.045*	74.7	< 0.001*
Yes	63	89.2		93.2
RT field
IFI	13	66.7	0.058	92.3	0.649
ENI	78	86.9		87.1
Radiation dose
< 50 Gy	23	81.5	0.857	89.1	0.400
≥ 50 Gy	68	85.2		86.3

DSS disease-specific survival, LRFS local recurrence-free survival, RT radiotherapy, IFI involved field irradiation, ENI elective nodal irradiation
*p < 0.05

ISSN: 1748-717X