Table 3 Univariate and multivariable linear regression of log-transformed post-SBRT absolute lymphocyte count

Age (years)

− 0.001

− 0.004 to 0.002

0.535

Sex (male vs female)

− 0.012

− 0.042 to 0.019

0.440

ECOG (0 vs 1–2)

− 0.006

− 0.038 to 0.025

0.683

Disease extent (BRPC vs LAPC)

− 0.002

− 0.035 to 0.030

0.892

Induction CT duration (months)

− 0.006

− 0.020 to 0.007

0.357

Log₁₀PTV

− 0.13

− 0.216 to − 0.037

0.006

− 0.15

− 0.30 to − 0.005

0.042

VertebralV20 (%)

− 0.013

− 0.025 to − 0.001

0.032

VertebralV17.5 (%)

− 0.009

− 0.017 to 0.001

0.022

VertebralV15 (%)

− 0.006

− 0.011 to − 0.001

0.013

− 0.026

− 0.044 to − 0.009

0.003

VertebralV12.5 (%)

− 0.004

− 0.008 to − 0.001

0.019

VertebralV10 (%)

− 0.003

− 0.005 to − 2e−5

0.049

VertebralV7.5 (%)

− 0.002

− 0.004 to 4e−5

0.054

VertebralV5 (%)

− 0.003

− 0.005 to − 3e−4

0.027

VertebralV2.5 (%)

− 0.003

− 0.005 to − 2e−4

0.031

− 0.011

− 0.020 to − 0.002

0.015

Mean vertebral dose (Gy)

− 0.001

− 4e−4 to − 5e−5

0.014

SpleenV15 (%)

− 0.005

− 0.011 to 0.001

0.090

SpleenV12.5 (%)

0.002

− 0.007 to 1e−4

0.061

SpleenV10 (%)

− 0.002

− 0.005 to − 3e−4

0.027

− 0.006

− 0.013 to 8e−4

0.084

SpleenV7.5 (%)

− 0.002

− 0.003 to − 2e−4

0.028

SpleenV5 (%)

− 0.002

− 0.003 to − 2e−4

0.019

− 0.005

− 0.011 to 5e−4

0.072

SpleenV2.5 (%)

− 0.001

− 0.002 to 4e−5

0.058

Mean spleen dose (Gy)

1e−4

− 3e−4 to − 2e−5

0.021