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Table 2 Disease characteristics in relation with chemotherapy schedule in relation to chemotherapy schedule

From: Three weekly versus weekly concurrent cisplatin: safety propensity score analysis on 166 head and neck cancer patients

Disease characteristic

1w-CDDP (N.114)

3w-CDDP (N.52)

p

Entire series (%)

Histology

0.125

 

 Squamous

109 (95.6%)

52 (100%)

 

161 (97%)

 Other histology

5 (4.4%)

0 (0%)

 

5 (3%)

Site of the disease

0.001

 

 Oropharynx

72 (63.2%)

47 (90.4%)

 

119 (71.7%)

 Hypopharynx

23 (20.2%)

2 (3.8%)

 

25 (25.1%)

 Larynx

19 (16.7%)

3 (5.8%)

 

22 (13.3%)

Staging T (TNM 7th Ed)

0.057

 

 T1–T2

52 (45.6%)

32 (61.3%)

 

84 (50.6%)

 T3–T4

62 (54.4%)

20 (38.5%)

 

82 (49.4%)

Staging N (TNM 7th Ed)

0.024

 

 N0

16 (14%)

2 (3.8%)

 

18 (10.8%)

 N1

17 (14.9%)

6 (11.5%)

 

23 (13.9%)

 N2

80 (70.2%)

40 (76.9%)

 

120 (72.3%)

 N3

1 (0.9%)

4 (7.7%)

 

5 (3%)

Stage (AJCC 7th Ed)

0.009

 

 II

5 (4.4%)

1 (1.9%)

 

6 (3.6%)

 III

28 (24.6%)

3 (5.8%)

 

31 (18.7%)

 IV

81 (71.1%)

48 (92.3%)

 

129 (77.7%)

HPV

0.000

 

 Positive

12 (10.5%)

32 (61.5%)

 

44 (26.5%)

 Negative

11 (9.6%)

5 (9.6%)

 

16 (9.6%)

 ND

91 (79.8%)

15 (28.8%)

 

106 (63.9%)

  1. HPV human papilloma virus, TNM tumor, node, metastases, AJCC American Joint Committee on Cancer, 1w-CDDP weekly Cisplatin, 3w-CDDP three-weekly Cisplatin