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Table 1 Patient and treatment characteristics

From: Proton therapy with a fixed beamline for skull-base chordomas and chondrosarcomas: outcomes and toxicity

Patient characteristics

Number (or %)

Total patients

31

Median follow-up time in months

21 [4–52]

Gender

 

Female

20 (64.5%)

Male

11 (35.5%)

Median age in years

50 [27–71]

Median ECOG status

1 [0–3]

Histology/Radiological diagnosis

Chordoma

23 (74.2%)

Chondrosarcoma

8 (25.8%)

Surgery

Unresectable

6 (19.4%)

R1

10 (32.2%)

R2

15 (48.4%)

Indication for irradiation

Primary

6 (19.4%)

Adjuvant

18 (58.0%)

Progression/recurrence (including re-RT)

7 (22.6%) / 4 (12.9%)

Critical OAR involvement

Brainstem

6

Visual pathway

7

Spinal cord

1

Cranial nerves

8

Hypophysis

10

Involved anatomical site

 

Clivus

26

Pyramids

3

Ethmoidal bone

4

Orbit

1

Cervical spine

3

Nasal cavity

3

Symptoms

Headache

15

Visual disfunction (diplopia)

10

Facial paresis

2

Motion paresis

3

Otalgia

3

Ptosis

2