Table 3 Local control rates after EBRT and results of univariate and multivariate analyses

Age

 < 70 years vs. ≥ 70 years

89 vs. 71

84 vs. 69

2.32 (1.68–3.21)

2.34 (1.62–3.40)

 < 0.001

Sex

Female vs. male

88 vs. 78

86 vs. 73

1.92 (1.35–2.72)

1.15 (0.76–1.73)

0.514

Primary tumor sites

Moderately unfavorable vs. favorable

77 vs. 89

77 vs. 87

0.40 (0.26–0.64)

0.49 (0.29–0.81)

0.006

Moderately unfavorable vs. unfavorable

77 vs. 62

77 vs. 47

1.84 (1.15–2.95)

2.28 (1.34–3.86)

0.002

EBRT sites

Vertebral bone vs. other bone

88 vs. 75

86 vs. 69

2.34 (1.69–3.25)

1.78 (1.24–2.57)

0.002

EBRT dose (BED₁₀)

 ≥ 39.0 Gy vs. < 39.0 Gy

85 vs. 68

82 vs. 60

2.02 (1.34–3.05)

2.08 (1.31–3.30)

0.002

Post-EBRT BMAs

Yes vs. no

88 vs. 74

86 vs. 67

2.49 (1.79–3.46)

1.94 (1.34–2.83)

 < 0.001

Post-EBRT ATs

Yes vs. no

88 vs. 70

84 vs. 65

2.41 (1.73–3.36)

1.58 (1.08–2.31)

0.018

Bone cortex destruction

Yes vs. no

80 vs. 90

77 vs. 84

0.70 (0.46–1.05)

0.67 (0.42–1.06)

0.084

Pre-EBRT ATs

Yes vs. no

85 vs. 80

80 vs. 78

1.24 (0.89–1.71)

–

–