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Table 3 Univariate analysis of prognostic factors associated with LPFS in patients with ESCC treated with chemoradiotherapy

From: Development and validation of a radiomics-based model to predict local progression-free survival after chemo-radiotherapy in patients with esophageal squamous cell cancer

Variables Training cohort p Validation cohort p
HR 95% CI p HR 95% CI p
Age 0.987 0.967–1.007 0.202 0.984 0.957–1.011 0.252
Gender 1.639 1.014–2.650 0.044 1.198 0.652–2.202 0.560
Tumor location 1.120 0.851–1.473 0.419 1.289 0.917–1.812 0.143
T stage 2.015 1.453–2.793 < 0.001 1.943 1.227–3.077 0.005
N stage 1.867 1.446–2.410 < 0.001 1.765 1.215–2.563 0.003
Clinical stage 2.194 1.581–3.044  < 0.001 2.309 1.440–3.704 0.001
Radiation dose 0.965 0.923–1.009 0.118 0.996 0.921–1.078 0.927
LDH 1.641 1.116–2.414 0.012 1.369 0.778–2.408 0.276
NLR 1.069 0.965–1.184 0.199 1.015 0.901–1.142 0.810
PLR 1.001 0.999–1.003 0.177 1.001 0.999–1.004 0.377
CR status 0.128 0.072–0.228 < 0.001 0.295 0.157–0.556 < 0.001