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Table 3 Univariate analysis of prognostic factors associated with LPFS in patients with ESCC treated with chemoradiotherapy

From: Development and validation of a radiomics-based model to predict local progression-free survival after chemo-radiotherapy in patients with esophageal squamous cell cancer

Variables

Training cohort p

Validation cohort p

HR

95% CI

p

HR

95% CI

p

Age

0.987

0.967–1.007

0.202

0.984

0.957–1.011

0.252

Gender

1.639

1.014–2.650

0.044

1.198

0.652–2.202

0.560

Tumor location

1.120

0.851–1.473

0.419

1.289

0.917–1.812

0.143

T stage

2.015

1.453–2.793

< 0.001

1.943

1.227–3.077

0.005

N stage

1.867

1.446–2.410

< 0.001

1.765

1.215–2.563

0.003

Clinical stage

2.194

1.581–3.044

 < 0.001

2.309

1.440–3.704

0.001

Radiation dose

0.965

0.923–1.009

0.118

0.996

0.921–1.078

0.927

LDH

1.641

1.116–2.414

0.012

1.369

0.778–2.408

0.276

NLR

1.069

0.965–1.184

0.199

1.015

0.901–1.142

0.810

PLR

1.001

0.999–1.003

0.177

1.001

0.999–1.004

0.377

CR status

0.128

0.072–0.228

< 0.001

0.295

0.157–0.556

< 0.001