Table 2 Prognostic factors for overall survival

Treatment

< 0.001

0.002

0.002

 Chemotherapy alone

Reference

Reference

Reference

 Combined modality therapy

0.689 (0.575–0.827)

0.742 (0.614–0.897)

0.721 (0.585–0.889)

Age, y

< 0.001

< 0.001

< 0.001

 18–39

Reference

Reference

Reference

 40–64

2.996 (1.755–5.113)

3.648 (2.093–6.359)

3.342 (1.794–6.223)

 65+

11.806 (6.980-19.968)

13.448 (7.792–23.210)

13.696 (7.405–25.333)

Sex

0.081

0.774

 Male

Reference

1.031 (0.836–1.272)

 Female

1.173 (0.981–1.404)

Year of diagnosis

< 0.001

< 0.001

< 0.001

 1983–2001

Reference

Reference

Reference

 2002–2016

0.658 (0.543–0.797)

0.612 (0.503–0.746)

0.630 (0.503–0.788)

Race

0.119

0.211

 White

Reference

Reference

 Black

0.786 (0.535–1.155)

0.724 (0.454–1.154)

 Other

0.785 (0.601–1.027)

0.818 (0.596–1.124)

Stage

< 0.001

< 0.001

< 0.001

 I

Reference

Reference

Reference

 II

0.943 (0.771–1.153)

0.922 (0.750–1.134)

0.976 (0.779–1.222)

 III

1.713 (1.195–2.455)

1.502 (1.042–2.164)

1.869 (1.144–3.055)

 IV

2.368 (1.775–3.161)

2.170 (1.610–2.925)

1.865 (1.276–2.723)

Marital status

0.001

< 0.001

0.416

 Married

Reference

Reference

Reference

 Other

1.347 (1.121–1.619)

1.408 (1.168–1.698)

1.093 (0.882–1.356)