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Table 3 Multivariate analysis of clinical outcomes

From: BRAF mutation correlates with worse local–regional control following radiation therapy in patients with stage III melanoma

Variable

Local–Regional (LN) Control

P

DMFS

P

RFS

P

OS

P

BRAF status

 Negative

–

0.02

–

0.94

–

0.46

–

0.94

 Positive

4.49 (1.3–15.5)

 

0.98 (0.55–1.7)

 

1.23 (0.71–2.1)

 

1.02 (0.55–1.9)

 

# of LNs positive

 < 4

–

0.03

–

0.07

–

0.04

–

0.01

 ≥ 4

2.79 (1.1–6.9)

 

1.80 (0.95–3.4)

 

1.87 (1.0–3.4)

 

2.26 (1.18–4.3)

 

Adjuvant systemic Tx

 No

  

–

0.09

–

0.04

  

 Yes

  

0.62 (0.35–1.1)

 

0.57 (0.3–0.96)

   
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Radiation Oncology

ISSN: 1748-717X

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