Table 4 Characteristics of patients with intracranial meningioma who underwent LINAC-based radiation treatment according to the presence of PTBE before and after propensity score matching based on patient sex, patient age, tumor location, GTV, and BED
| Characteristics | Before propensity score matching | After propensity score matching | ||||
|---|---|---|---|---|---|---|
|
PTBE (−) (n = 91) |
PTBE (+) (n = 15) | p |
PTBE (−) (n = 30) |
PTBE (+) (n = 15) | p | |
| Sex, female, n (%) | 70 (76.9) | 12 (80.0) | 0.792 | 23 (76.7) | 12 (80.0) | 0.800 |
| Age, mean ± SD, y | 62.4 ± 12.2 | 69.3 ± 9.3 | 0.039 | 68.2 ± 11.0 | 69.3 ± 9.3 | 0.741 |
| Location, n (%) | 0.730 | 0.777 | ||||
| Convexity | 30 (33.0) | 6 (40.0) | 13 (43.3) | 6 (40.0) | ||
| Parasagittal or parafalcine | 19 (20.9) | 5 (33.3) | 10 (33.3) | 5 (33.3) | ||
| Sphenoid ridge | 9 (9.9) | 1 (6.7) | 3 (10.0) | 1 (6.7) | ||
| Cerebellopontine angle | 11 (12.1) | 2 (13.3) | 1 (3.3) | 2 (13.3) | ||
| Posterior fossa | 8 (8.8) | 1 (6.7) | 3 (10.0) | 1 (6.7) | ||
| Parasellar or petroclival | 11 (12.1) | 0 | 0 | 0 | ||
| Other | 3 (3.3) | 0 | 0 | 0 | ||
| GTV, mean ± SD, cc | 7.6 ± 9.5 | 11.8 ± 9.4 | 0.118 | 9.5 ± 12.2 | 11.8 ± 9.4 | 0.523 |
| BED (α/β = 3), mean ± SD, Gy | 89.0 ± 18.4 | 92.6 ± 21.0 | 0.497 | 93.3 ± 19.9 | 92.6 ± 21.0 | 0.905 |
| Classification of mean skull HU, n (%) | 0.069 | 0.447 | ||||
| Hypothetical normal (> 712.4) | 49 (53.8) | 4 (26.7) | 13 (43.3) | 4 (26.7) | ||
| Hypothetical osteopenia > 611.7 and ≤ 712.4) | 10 (11.0) | 1 (6.7) | 3 (10.0) | 1 (6.7) | ||
| Hypothetical osteoporosis (≤ 611.7) | 32 (35.2) | 10 (66.7) | 14 (46.7) | 10 (66.7) | ||