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Table 4 Characteristics of patients with intracranial meningioma who underwent LINAC-based radiation treatment according to the presence of PTBE before and after propensity score matching based on patient sex, patient age, tumor location, GTV, and BED

From: Effect of osteoporotic conditions on the development of peritumoral brain edema after LINAC-based radiation treatment in patients with intracranial meningioma

Characteristics

Before propensity score matching

After propensity score matching

PTBE (−)

(n = 91)

PTBE (+)

(n = 15)

p

PTBE (−)

(n = 30)

PTBE (+)

(n = 15)

p

Sex, female, n (%)

70 (76.9)

12 (80.0)

0.792

23 (76.7)

12 (80.0)

0.800

Age, mean ± SD, y

62.4 ± 12.2

69.3 ± 9.3

0.039

68.2 ± 11.0

69.3 ± 9.3

0.741

Location, n (%)

  

0.730

  

0.777

Convexity

30 (33.0)

6 (40.0)

 

13 (43.3)

6 (40.0)

 

 Parasagittal or parafalcine

19 (20.9)

5 (33.3)

 

10 (33.3)

5 (33.3)

 

 Sphenoid ridge

9 (9.9)

1 (6.7)

 

3 (10.0)

1 (6.7)

 

 Cerebellopontine angle

11 (12.1)

2 (13.3)

 

1 (3.3)

2 (13.3)

 

 Posterior fossa

8 (8.8)

1 (6.7)

 

3 (10.0)

1 (6.7)

 

 Parasellar or petroclival

11 (12.1)

0

 

0

0

 

 Other

3 (3.3)

0

 

0

0

 

GTV, mean ± SD, cc

7.6 ± 9.5

11.8 ± 9.4

0.118

9.5 ± 12.2

11.8 ± 9.4

0.523

BED (α/β = 3), mean ± SD, Gy

89.0 ± 18.4

92.6 ± 21.0

0.497

93.3 ± 19.9

92.6 ± 21.0

0.905

Classification of mean skull HU, n (%)

  

0.069

  

0.447

 Hypothetical normal (> 712.4)

49 (53.8)

4 (26.7)

 

13 (43.3)

4 (26.7)

 

 Hypothetical osteopenia > 611.7 and ≤ 712.4)

10 (11.0)

1 (6.7)

 

3 (10.0)

1 (6.7)

 

 Hypothetical osteoporosis (≤ 611.7)

32 (35.2)

10 (66.7)

 

14 (46.7)

10 (66.7)

 
  1. LINAC, linear accelerator; PTBE, peritumoral brain edema; GTV, gross tumor volume; BED, biologically equivalent dose; SD, standard deviation; Gy, gray; HU, Hounsfield unit