Univariate analysis | Multivariate analysis | |||
---|---|---|---|---|
Variable | HR (95% CI) | p | HR (95% CI) | p |
Sex | ||||
Male | Reference | Reference | ||
Female | 1.08 (0.30–3.88) | 0.905 | 0.64 (0.15–2.71) | 0.543 |
Age (per 1 year increase) | 1.07 (1.02–1.13) | 0.005 | 1.08 (1.01–1.15) | 0.032 |
BMI (per 1 BMI increase) | 0.97 (0.82–1.14) | 0.722 | 1.09 (0.88–1.35) | 0.419 |
Classification of mean skull HU | ||||
Hypothetical normal | Reference | Reference | ||
Hypothetical osteopenia | 1.67 (0.17–16.13) | 0.657 | 3.22 (0.23–45.58) | 0.387 |
Hypothetical osteoporosis | 5.45 (1.48–20.03) | 0.011 | 5.20 (1.11–24.46) | 0.037 |
Location | 0.70 (0.49–1.00) | 0.050 | 0.70 (0.46–1.06) | 0.094 |
GTV (per 1 cc increase) | 1.08 (1.02–1.15) | 0.010 | 1.12 (1.04–1.21) | 0.004 |
BED (α/β = 3) (per 1 Gy increase) | 1.01 (0.98–1.03) | 0.665 | 1.02 (0.97–1.06) | 0.484 |
Fractionation (per 1 fraction increase) | 0.94 (0.85–1.03) | 0.179 | 0.90 (0.71–1.16) | 0.415 |
Hypertension | ||||
No | Reference | Reference | ||
Yes | 1.13 (0.41–3.15) | 0.815 | 0.66 (0.17–2.61) | 0.554 |
Diabetes | ||||
No | Reference | Reference | ||
Yes | 1.05 (0.29–3.79) | 0.937 | 0.42 (0.09–2.03) | 0.278 |