Dosimetric comparison and biological evaluation of fixed-jaw intensity-modulated radiation therapy for T-shaped esophageal cancer

Table 3 Comparisons of dosimetric parameters of PTV

	JT IMRT	SJ IMRT	JT VMAT	FJ IMRT	ANOVA p value	Post hoc p value
	JT IMRT	SJ IMRT	JT VMAT	FJ IMRT	ANOVA p value	FJ IMRT versus JT IMRT	FJ IMRT versus SJ IMRT	FJ IMRT versus JT VMAT
PTV-G
D₂ (Gy)	63.65 ± 0.73	63.62 ± 0.75	63.79 ± 0.80	63.67 ± 0.66	0.800	0.459	0.347	0.504
D₉₈ (Gy)	59.43 ± 0.38	59.47 ± 0.37	59.45 ± 0.34	59.42 ± 0.33	0.930	0.775	0.864	0.665
CI	0.84 ± 0.03	0.84 ± 0.03	0.84 ± 0.05	0.84 ± 0.03	0.889	0.846	0.599	0.912
HI	0.07 ± 0.02	0.07 ± 0.02	0.08 ± 0.02	0.07 ± 0.01	0.846	0.827	0.561	0.771
PTV-C
D₂ (Gy)	62.89 ± 0.80	62.83 ± 0.81	63.78 ± 0.86	63.80 ± 0.88	< 0.001	< 0.001	< 0.001	0.922
D₉₈ (Gy)	50.61 ± 0.73	50.60 ± 0.75	50.58 ± 0.80	50.62 ± 0.65	0.998	0.962	0.951	0.854

All values are shown as the mean ± standard deviation
PTV, planning target volume; JT IMRT, jaw-tracking intensity-modulated radiation therapy; SJ IMRT, static jaw intensity-modulated radiation therapy; JT VMAT, jaw-tracking volumetric modulated arc therapy; FJ IMRT, fixed-jaw intensity-modulated radiation therapy; D_x, the minimum dose to the hottest x% of the PTV; CI, conformity index; HI, homogeneity index

ISSN: 1748-717X