Table 1 Clinical features of patients with LGGs stratified by MGMT status
Characteristics | n (%) | MGMT-pM n (%) | MGMT-non-pM n (%) |
|---|---|---|---|
Total | 268 | 115 (42.9) | 153 (57.1) |
Sex | 268 (100) | ||
Male | 152 (56.7) | 62 (40.8) | 90 (59.2) |
Female | 116 (43.3) | 53 (45.7) | 63 (54.3) |
Age (years) | 268 (100) | ||
≤ 40 | 153 (57.2) | 55 (35.9) | 98 (64.1) |
> 40 | 115 (42.8) | 60 (52.2) | 55 (47.8) |
Histopathology | 268 (100) | ||
A* | 220 (82.1) | 83 (37.7) | 137 (62.3) |
O | 48 (17.9) | 32 (66.7) | 16 (33.7) |
Seizure | 204 (76.1) | ||
Yes | 122 (59.5) | 33 (27.0) | 89 (63.0) |
No | 82 (40.5) | 25 (30.5) | 57 (69.5) |
Resection | 248 (92.5) | ||
Total | 115 (46.4) | 57 (49.6) | 58 (50.4) |
Subtotal | 133 (53.6) | 48 (36.1) | 85 (63.9) |
RT dose | 268 (100) | ||
High | 155 (57.8) | 64 (41.3) | 91 (58.7) |
Low | 113 (42.2) | 51 (45.1) | 62 (54.9) |
Chemotherapy | 260 (97.0) | ||
Yes | 87 (33.5) | 42 (48.3) | 45 (51.7) |
No | 173 (66.5) | 66 (38.2) | 107 (61.8) |
IDH muation | 250 (93.3) | ||
Yes | 206 (82.4) | 93 (45.1) | 113 (54.9) |
No | 44 (17.6) | 8 (18.2) | 36 (81.8) |
1p/19q codeletion | 161 (60.1) | ||
Yes | 63 (39.1) | 43 (68.3) | 20 (31.7) |
No | 98 (70.9) | 43 (43.9) | 55 (56.1) |