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Table 1 Dosimetric variations for the HRCTV, bladder, rectum, sigmoid and intestine between planning CT and pre-delivery CBCT

From: Intra-fractional dosimetric analysis of image-guided intracavitary brachytherapy of cervical cancer

  CT CBCT Variation Range of difference P
HRCTV
Volume (cc) 54.1 ± 17.2 53.1 ± 16.9  − 2.0 ± 3.3% 0.02–6.8  < 0.001
D90 (cGy) 606.4 ± 39.3 599.1 ± 45.8 1.2 ± 4.5% 0.1–79.1 0.120
D90 (EQD2, cGy) 813.0 ± 72.6 800.1 ± 83.6 1.2 ± 6.1% 0.1–156.0 0.139
Bladder      
Volume (cc) 81.4 ± 53.5 81.7 ± 48.0 7.9 ± 36.7% 0.3–146.1 0.957
D2cc (cGy) 391.6 ± 74.8 389.2 ± 71.9  − 0.6 ± 17.1% 1.8–167.8 0.810
D2cc (EQD2, cGy) 552.5 ± 151.1 542.6 ± 151.2 2.7 ± 26.6% 4.2–355.2 0.772
Rectum
Volume (cc) 46.2 ± 13.9 41.9 ± 15.5  − 6.9% ± 34.1% 0.02–22.5 0.001*
D2cc (cGy) 302.9 ± 84.4 327.0 ± 86.9 9.3 ± 14.6% 0.6–168.0 0.001*
D2cc (EQD2, cGy) 379.1 ± 157.1 425.7 ± 169.3 15.0 ± 24.0% 0.7–336.2 0.001*
Sigmoid
Volume (cc) 24.8 ± 15.72 24.28 ± 11.1 19.9 ± 68.2% 0.2–48.9 0.763
D2cc (cGy) 301.5 ± 85.8 312.5 ± 74.6 7.2 ± 20.5% 1.7–130.3 0.127
D2cc (EQD2, cGy) 376.9 ± 146.6 393.7 ± 130.4 11.4 ± 31.9% 2.8–210.4 0.192
Small intestine
Volume (cc) 401.0 ± 115.0 394.0 ± 145.7  − 0.5 ± 26.7% 2.3–360.7 0.705
D2cc (cGy) 411.2 ± 60.3 418.2 ± 83.4 1.5 ± 12.6% 0.8–138.8 0.422
D2cc (EQD2, cGy) 591.9 ± 130.9 614.2 ± 190.0 3.4 ± 20.7% 2.0–353.6 0.293
  1. Relative differences between parameters (volume, D90 and D2cc) from two images sets were calculated as Difference = (Valuepre − Valueplan)/Valueplan. A positive value means that the volume/dose obtained for pre-delivery image was higher than that on the plan image
  2. *P < 0.05