Skip to main content

Table 3 Summary of multivariate analysis of prognostic factors

From: Clinical outcomes and patterns of failure of head and neck mucosal melanoma treated with multiple treatment modalities

Endpoint

Variable

HR

95% CI for HR

P valuea

OS

Primary tumour site

  

0.003

 

Nasal cavity

1.467

(0.842, 2.555)

 
 

Paranasal sinus

2.974

(1.578, 6.350)

 
 

Oral cavity

2.404

(1.539, 4.986)

 
 

Others(reference)

1

  
 

Reoperation

0.733

(0.530, 1.015)

0.061

 

T classification

  

< 0.001

 

T3(reference)

1

  
 

T4a

3.073

(2.146, 4.401)

 
 

T4b

3.817

(1.854, 7.857)

 
 

Immunologic/targeted therapy

0.638

(0.435, 0.934)

0.021

DMFS

Irradiation technique

2.145

(1.158, 3.975)

0.015

 

T classification

  

< 0.001

 

T3(reference)

1

  
 

T4a

2.524

(1.560, 4.085)

 
 

T4b

4.025

(1.348, 12.018)

 
 

N classification

1.808

(1.037, 3.154)

0.037

DFS

T classification

  

0.001

 

T3(reference)

1

  
 

T4a

2.315

(1.466, 3.658)

 
 

T4b

3.016

(1.093, 8.326)

 
 

Node classification

2.298

(1.338, 3.948)

0.003

 

Irradiation technique

1.767

(0.978, 3.190)

0.059

 

Smoking

0.607

(0.355, 1.040)

0.069

 

Surgery

0.311

(0.104, 0.929)

0.036

LRRFS

T classification

  

0.015

 

T3(reference)

1

  
 

T4a

1.798

(1.131, 2.858)

 
 

T4b

2.978

(1.125, 7.878)

 
 

Node classification

1.916

(1.097, 3.345)

0.022

 

Irradiation technique

1.660

(0.941, 2.949)

0.08

  1. aStatistically significant results are shown in bold. *P values < 0.05 are highlighted in bold
  2. OS, overall survival; DMFS, distant metastasis-free survival; DFS: disease-free survival probability; LRRFS, local regional relapse free survival; HR, hazard ratio; CI, confidence interval