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Table 3 Summary of multivariate analysis of prognostic factors

From: Clinical outcomes and patterns of failure of head and neck mucosal melanoma treated with multiple treatment modalities

Endpoint Variable HR 95% CI for HR P valuea
OS Primary tumour site    0.003
  Nasal cavity 1.467 (0.842, 2.555)  
  Paranasal sinus 2.974 (1.578, 6.350)  
  Oral cavity 2.404 (1.539, 4.986)  
  Others(reference) 1   
  Reoperation 0.733 (0.530, 1.015) 0.061
  T classification    < 0.001
  T3(reference) 1   
  T4a 3.073 (2.146, 4.401)  
  T4b 3.817 (1.854, 7.857)  
  Immunologic/targeted therapy 0.638 (0.435, 0.934) 0.021
DMFS Irradiation technique 2.145 (1.158, 3.975) 0.015
  T classification    < 0.001
  T3(reference) 1   
  T4a 2.524 (1.560, 4.085)  
  T4b 4.025 (1.348, 12.018)  
  N classification 1.808 (1.037, 3.154) 0.037
DFS T classification    0.001
  T3(reference) 1   
  T4a 2.315 (1.466, 3.658)  
  T4b 3.016 (1.093, 8.326)  
  Node classification 2.298 (1.338, 3.948) 0.003
  Irradiation technique 1.767 (0.978, 3.190) 0.059
  Smoking 0.607 (0.355, 1.040) 0.069
  Surgery 0.311 (0.104, 0.929) 0.036
LRRFS T classification    0.015
  T3(reference) 1   
  T4a 1.798 (1.131, 2.858)  
  T4b 2.978 (1.125, 7.878)  
  Node classification 1.916 (1.097, 3.345) 0.022
  Irradiation technique 1.660 (0.941, 2.949) 0.08
  1. aStatistically significant results are shown in bold. *P values < 0.05 are highlighted in bold
  2. OS, overall survival; DMFS, distant metastasis-free survival; DFS: disease-free survival probability; LRRFS, local regional relapse free survival; HR, hazard ratio; CI, confidence interval