|
Endpoint
|
Variable
|
HR
|
95% CI for HR
|
P valuea
|
|---|
|
OS
|
Primary tumour site
| | |
0.003
|
| |
Nasal cavity
|
1.467
|
(0.842, 2.555)
| |
| |
Paranasal sinus
|
2.974
|
(1.578, 6.350)
| |
| |
Oral cavity
|
2.404
|
(1.539, 4.986)
| |
| |
Others(reference)
|
1
| | |
| |
Reoperation
|
0.733
|
(0.530, 1.015)
|
0.061
|
| |
T classification
| | |
< 0.001
|
| |
T3(reference)
|
1
| | |
| |
T4a
|
3.073
|
(2.146, 4.401)
| |
| |
T4b
|
3.817
|
(1.854, 7.857)
| |
| |
Immunologic/targeted therapy
|
0.638
|
(0.435, 0.934)
|
0.021
|
|
DMFS
|
Irradiation technique
|
2.145
|
(1.158, 3.975)
|
0.015
|
| |
T classification
| | |
< 0.001
|
| |
T3(reference)
|
1
| | |
| |
T4a
|
2.524
|
(1.560, 4.085)
| |
| |
T4b
|
4.025
|
(1.348, 12.018)
| |
| |
N classification
|
1.808
|
(1.037, 3.154)
|
0.037
|
|
DFS
|
T classification
| | |
0.001
|
| |
T3(reference)
|
1
| | |
| |
T4a
|
2.315
|
(1.466, 3.658)
| |
| |
T4b
|
3.016
|
(1.093, 8.326)
| |
| |
Node classification
|
2.298
|
(1.338, 3.948)
|
0.003
|
| |
Irradiation technique
|
1.767
|
(0.978, 3.190)
|
0.059
|
| |
Smoking
|
0.607
|
(0.355, 1.040)
|
0.069
|
| |
Surgery
|
0.311
|
(0.104, 0.929)
|
0.036
|
|
LRRFS
|
T classification
| | |
0.015
|
| |
T3(reference)
|
1
| | |
| |
T4a
|
1.798
|
(1.131, 2.858)
| |
| |
T4b
|
2.978
|
(1.125, 7.878)
| |
| |
Node classification
|
1.916
|
(1.097, 3.345)
|
0.022
|
| |
Irradiation technique
|
1.660
|
(0.941, 2.949)
|
0.08
|
- aStatistically significant results are shown in bold. *P values < 0.05 are highlighted in bold
- OS, overall survival; DMFS, distant metastasis-free survival; DFS: disease-free survival probability; LRRFS, local regional relapse free survival; HR, hazard ratio; CI, confidence interval
