|
Parameters
|
AUC
|
SE
|
95% CI
|
Z statistic
|
P value
|
Youden index
|
Associated criterion
|
Sensitivity (%)
|
Specificity (%)
|
|---|
|
SUVmax-Tpost
|
0.720
|
0.0804
|
0.563–0.846
|
2.743
|
0.0061
|
0.4409
|
≤ 4.42
|
78.57
|
65.52
|
|
MTV-Tpost
|
0.819
|
0.0647
|
0.672–0.920
|
4.927
|
< 0.0001
|
0.5172
|
≤ 5.076
|
100.00
|
51.72
|
|
TLG-Tpost
|
0.828
|
0.0630
|
0.682–0.925
|
5.204
|
< 0.0001
|
0.5517
|
≤ 14.65
|
100.00
|
55.17
|
|
ΔSUVmax-T
|
0.752
|
0.0752
|
0.598–0.869
|
3.346
|
0.0008
|
0.4874
|
≥ 0.7229
|
86.67
|
62.07
|
|
ΔMTV-T
|
0.685
|
0.101
|
0.528–0.817
|
1.836
|
0.0663
|
0.4299
|
≥ 0.8937
|
53.33
|
89.66
|
|
ADCduring
|
0.880
|
0.0602
|
0.704–0.962
|
6.325
|
< 0.0001
|
0.7029
|
> 2.52
|
83.33
|
86.96
|
|
ADCpost
|
0.771
|
0.0842
|
0.588–0.900
|
3.114
|
0.0018
|
0.6234
|
> 2.68
|
90.91
|
71.43
|
|
ΔADCduring
|
0.851
|
0.0639
|
0.691–0.949
|
5.504
|
< 0.0001
|
0.6522
|
> 0.53
|
100.0
|
65.22
|
|
Combined model*
|
0.914
|
0.0518
|
0.759–0.983
|
7.987
|
< 0.0001
|
0.7636
|
≤ 0.475
|
90.00
|
86.36
|
- P values less than 0.05 are indicated in bold italics
- *Predicted probability of the combined model: P = e^(7.325 + 0.244*TLG-Tpost-3.774*ADCduring)/(1 + e^(7.325 + 0.244*TLG-Tpost-3.774*ADCdur ing))
- DW-MRI diffusion-weighted magnetic resonance imaging; 18F-FDG-PET/CT 18F-Fluorodeoxyglucose-positron emission tomography/computed tomography; pCR-T complete response of primary tumor; SUVmax maximum standard uptake value; MTV metabolic tumor volume; TLG total lesion glycolysis; ADC apparent diffusion coefficient; ROC receiver operating characteristic; AUC areas under the curve; SE standard error; CI confidence interval
