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Table 1 Patient and tumor characteristics

From: Salvage re-irradiation using stereotactic body radiation therapy for locally recurrent prostate cancer: the impact of castration sensitivity on treatment outcomes

 

All patients (n = 30)

Castrate-resistant (n = 11)

Castrate-sensitive (n = 19)

Age, years

Median (range)

71 (56–83)

72 (56–83)

69 (57–80)

Pre-salvage PSA, ng/ml

Median (range)

3.63 (0.05–77)

3.16 (0.05–12.8)

4.1 (0.65–77)

Pre-salvage imaging, n (%)

  

Ga68 PSMA PET

30 (100%)

11 (100%)

19 (100%)

mpMRI

11 (37%)

4 (36%)

7 (37%)

Location of local recurrence, n (%)

  

Prostate-only

18 (60%)

8 (73%)

10 (53%)

Prostate and SV

10 (33%)

3 (27%)

7 (37%)

SV-only

2 (7%)

0 (0%)

2 (11%)

Staging at recurrence, n (%)

  

T-stage ≥ T3 (locally advanced)

14 (47%)

6 (55%)

8 (42%)

Node positive (regional)

7 (23%)

3 (27%)

4 (21%)

Oligo-metastatic

1 (3%)

1 (9%)

0 (0%)

Histologic confirmation, n (%)

  

Yes

18 (60%)

6 (55%)

12 (63%)

Median Gleason score1 (range)

9 (8–10)

  
  1. Note that 83% of patients had high-risk features at recurrence (either castrate-resistant, Gleason ≥ 8, T-stage ≥ T3, or node positive)
  2. SBRT, stereotactic body radiation therapy; PSA, prostate specific antigen; mpMRI, multi-parametric magnetic resonance imaging; Ga68-PSMA, gallium-68 prostate specific membrane antigen positron; PET, positron emission tomography; SV, seminal vesicles
  3. 1Data was available for 8 patients