Table 2 Summary of the PTV dosimetry parameters of the reoptimized treatment plans (Plan_FD and Plan_UIH) and the original clinical treatment plans (Plan_Manual). All of the values are reported as the mean ± standard deviation
Site/structure | Dosimetric Indices | Plan | Value | Comparison (paired t test) |
|---|---|---|---|---|
Rectal/PTV | V100 (%) | Manual | 97.41 ± 1.91 | – |
FD | 96.37 ± 2.98 | p = 0.35 | ||
UIH | 96.49 ± 2.72 | p = 0.33 | ||
D95 (cGy) | Manual | 5088 ± 77 | – | |
FD | 5028 ± 66 | p = 0.09 | ||
UIH | 5042 ± 70 | p = 0.11 | ||
D2 (cGy) | Manual | 5349 ± 177 | – | |
FD | 5384 ± 167 | p = 0.08 | ||
UIH | 5383 ± 160 | p = 0.08 | ||
Gamma Pass Rate (3 mm/3%) | FD | 97.16 ± 2.43 | – | |
UIH | 97.20 ± 2.34 | – | ||
Conformity Index (CI) | Manual | 0.78 ± 0.23 | – | |
FD | 0.78 ± 0.23 | p = 0.52 | ||
UIH | 0.78 ± 0.23 | p = 0.48 | ||
Homogeneity Index (HI) | Manual | 0.10 ± 0.08 | – | |
FD | 0.10 ± 0.06 | p = 0.64 | ||
UIH | 0.10 ± 0.06 | p = 0.63 | ||
NPC/PTV70.4 | V100 (%) | Manual | 93.39 ± 0.94 | – |
FD | 92.75 ± 2.03 | p = 0.39 | ||
UIH | 92.28 ± 2.00 | p = 0.12 | ||
D95 (cGy) | Manual | 6984 ± 25 | – | |
FD | 6978 ± 31 | p = 0.66 | ||
UIH | 6962 ± 32 | p = 0.16 | ||
D2 (cGy) | Manual | 7425 ± 270 | – | |
FD | 7445 ± 287 | p = 0.17 | ||
UIH | 7423 ± 276 | p = 0.92 | ||
Gamma Pass Rate (3 mm/3%) | FD | 99.20 ± 1.07 | – | |
UIH | 96.35 ± 2.34 | – | ||
Conformity Index (CI) | Manual | 0.72 ± 0.05 | – | |
FD | 0.70 ± 0.04 | p = 0.23 | ||
UIH | 0.70 ± 0.06 | p = 0.24 | ||
Homogeneity Index (HI) | Manual | 0.12 ± 0.05 | – | |
FD | 0.12 ± 0.05 | p = 0.33 | ||
UIH | 0.12 ± 0.04 | p = 0.58 |