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Table 4 Volume size changes according to hippocampi groups

From: Role of hippocampal location and radiation dose in glioblastoma patients with hippocampal atrophy

 

# of patients

Homolateral

Contralateral

VL (mm3/Gy)

%L (%/Gy)

VL (mm3/Gy)

%L (%/Gy)

(a)

Group 1

6

− 124

+ 1.5

+ 172

+ 4.0

Group 2

13

− 15

− 0.51

+ 15

+ 4.3

Group 3

30

− 19.7

− 0.04

− 19.7

− 0.52

 

D40% ≤ 7.4 Gy

7.4 Gy < D40% ≤ 30 Gy

30 Gy < D40% ≤ 50 Gy

D40% > 50 Gy

(b)

Slope VL

+ 94.3 mm3/Gy

− 8.6 mm3/Gy

− 45.4 mm3/Gy

− 112.2 mm3/Gy

Slope %L

+ 2.7 %/Gy

− 0.44 %/Gy

− 1.13 %/Gy

− 5.55 %/Gy

  1. (a) Slope values of the volume lost (VL, mm3/Gy) or percentage of volume lost (L − %/Gy) in each hippocampus (homo or contralateral to the tumor) and for the three groups stratified by D40% in both hippocampi: In group 1 (G1: n = 6), in both hippocampi, the D40% was < 7.4 Gy; in group 2 (G2: n = 13), the Hcontra D40% was < 7.4 Gy; in group 3 (G3: n = 30), the D40% for both hippocampi was > 7.4 Gy. (b) Slope values of volume lost: The volume lost (VL) or percentage of volume lost (%L − %/Gy) according to the dose for both hippocampi between the reference MRI (dosimetric MRI) and last MRI during follow-up