Role of hippocampal location and radiation dose in glioblastoma patients with hippocampal atrophy

Radiation Oncology

Table 3 Median dose in the hippocampi

		Dmean	Dmax	D10%	D20%	D30%	D40%	D50%	D60%	D70%	D80%	D90%	D100%
(a)
Homolateral hippocampus	Min	1.30	1.86	1.51	1.40	1.34	1.30	1.27	1.24	1.20	1.16	1.12	1.03
	Max	61.12	63.49	62.82	62.16	61.51	61.35	61.18	60.97	60.75	60.53	60.25	59.65
	median	53.85	59.99	59.37	59.10	58.74	57.94	56.63	53.93	50.87	45.02	38.21	35.33
Contralateral hippocampus	Min	1.26	1.99	1.52	1.37	1.31	1.27	1.23	1.10	0.94	0.83	0.73	0.58
	Max	46.88	61.07	58.33	56.23	52.73	49.68	46.27	42.65	40.35	38.34	37.62	36.71
	median	13.89	33.26	20.41	16.42	14.57	11.50	11.15	10.87	10.74	10.60	9.72	3.80

			Dmean	Dmax	D10%	D20%	D30%	D40%	D50%	D60%	D70%	D80%	D90%	D100%
(b)
Group 1	Homolateral hippocampus	Min	1.30	1.86	1.51	1.40	1.34	1.30	1.27	1.24	1.20	1.16	1.12	1.03
		Max	5.06	17.63	8.47	7.39	6.02	5.06	4.41	3.91	3.58	3.27	2.98	1.71
		median	2.78	6.32	4.77	3.69	2.64	2.30	2.19	2.04	1.94	1.80	1.71	1.35
	Contralateral hippocampus	Min	1.26	1.99	1.52	1.37	1.31	1.27	1.23	1.19	1.11	1.00	0.90	0.77
		Max	4.80	13.12	6.97	5.77	5.20	4.74	4.36	4.08	3.81	3.52	3.22	1.05
		median	1.99	5.47	3.50	2.11	1.73	1.60	1.47	1.38	1.30	1.20	1.12	0.99
Group 2	Homolateral hippocampus	Min	8.44	17.94	10.78	10.65	10.35	8.56	7.87	7.87	4.12	3.27	2.44	4.79
		Max	59.96	61.83	61.08	60.93	60.78	60.56	60.32	60.32	59.72	59.22	58.88	54.03
		median	35.54	54.95	45.74	43.05	40.98	38.47	34.90	34.90	22.06	17.04	15.34	7.50
	Contralateral hippocampus	Min	3.28	11.30	5.31	3.56	3.15	2.25	1.31	1.10	0.94	0.83	0.73	0.58
		Max	12.59	54.15	34.18	25.58	13.73	7.40	6.22	5.94	5.51	4.91	4.16	3.57
		median	6.16	21.06	10.17	7.43	6.59	5.14	4.70	3.30	3.11	2.94	2.75	2.46
Group 3	Homolateral hippocampus	Min	17.60	25.00	21.30	20.01	19.13	18.17	17.35	16.52	15.75	14.70	9.26	9.25
		Max	61.12	63.49	62.82	62.16	61.51	61.35	61.18	60.97	60.75	60.53	60.25	59.65
		median	57.87	60.77	60.18	59.72	59.31	59.25	58.98	58.73	57.98	56.79	55.49	44.26
	Contralateral hippocampus	Min	8.17	16.02	11.76	11.42	10.64	8.12	5.86	4.61	3.63	2.80	2.21	2.31
		Max	46.88	61.07	58.33	56.23	52.73	49.68	46.27	42.65	40.35	38.34	37.62	36.71
		median	19.57	38.32	29.41	23.58	19.40	18.52	17.95	17.31	16.08	15.47	14.53	13.96

ISSN: 1748-717X