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Table 5 Dosimetric comparison of target and organs at risk between the spacer group and the control group after propensity score-matching

From: Phase II study of stereotactic body radiotherapy with hydrogel spacer for prostate cancer: acute toxicity and propensity score-matched comparison

 

Spacer (n = 39)

Control (n = 39)

P

Mean (± S.D.)

Mean (± S.D.)

Prostate, ml

39.2 (± 20.9)

39.3 (± 31.5)

1.00

Seminal vesicles, ml

13.1 (± 5.4)

10.1 (± 5.6)

0.02

PTV, ml

99.0 (± 37.2)

97.3 (± 49.2)

0.86

Rectum, ml

49.5 (± 22.3)

52.3 (± 15.8)

0.52

Bladder, ml

273.3 (± 133.6)

238.6 (± 119.3)

0.23

PTV mean, Gy

37.2 (± 0.3)

37.5 (± 0.4)

 < 0.01

PTV max, Gy

39.0 (± 0.6)

39.5 (± 0.8)

 < 0.01

Rectum mean, Gy

15.1 (± 1.3)

17.0 (± 1.3)

 < 0.01

Rectum max, Gy

36.9 (± 1.8)

38.7 (± 0.7)

 < 0.01

Rectum V100%, %

0.4 (± 0.7)

2.7 (± 1.6)

 < 0.01

Rectum V90%, %

2.3 (± 2.2)

8.5 (± 2.7)

 < 0.01

Rectum V80%, %

5.0 (± 3.5)

13.7 (± 3.4)

 < 0.01

Rectum V75%, %

6.9 (± 4.1)

16.6 (± 3.8)

 < 0.01

Rectum V50%, %

27.6 (± 5.6)

35.6 (± 5.2)

 < 0.01

Bladder mean, Gy

10.7 (± 3.8)

12.2 (± 3.5)

0.09

Bladder max, Gy

38.6 (± 0.6)

39.1 (± 0.7)

 < 0.01

Bladder V100%, %

3.8 (± 1.8)

4.2 (± 1.9)

0.39

Bladder V50%, %

22.9 (± 9.9)

25.2 (± 10.6)

0.32

Femur max, Gy

15.0 (± 1.5)

15.1 (± 1.8)

0.01

  1. Rectal volume including the rectal contents
  2. PTV planning target volume