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Table 1 \(\alpha /\beta\) ratios and SERs SERs taken from the corresponding linear quadratic curves in Fig. 6 for a 1 h exposure time. The SPION graph for H460 cells was unable to generate an accurate α value, which was constrained to be > 0

From: Impact of superparamagnetic iron oxide nanoparticles on in vitro and in vivo radiosensitisation of cancer cells

Cell line

SPION concentration

Control

23.5 μg/ml

\(\alpha\)(Gy−1)

\(\beta\)(Gy−2)

\(\alpha /\beta\)(Gy)

\(\alpha\)(Gy−1)

\(\beta\)(Gy−2)

\(\alpha /\beta\)(Gy)

SER for 8 Gy

SER for 10% SF

H460

0.049 ± 0.047

0.045 ± 0.006

1.08 ± 0.61

0

0.081 ± 0.005

0

1.18 ± 0.10

1.45 ± 0.36

MiaPaCa2

0.198 ± 0.049

0.024 ± 0.007

8.33 ± 1.81

0.094 ± 0.059

0.045 ± 0.092

2.09 ± 0.79

1.09 ± 0.10

1.05 ± 0.47

DU145

0.038 ± 0.064

0.051 ± 0.009

0.74 ± 0.72

0.196 ± 0.013

0.048 ± 0.002

4.06 ± 0.17

1.17 ± 0.07

1.23 ± 0.19

MCF7

0.118 ± 0.122

0.071 ± 0.017

1.67 ± 0.95

0.186 ± 0.132

0.055 ± 0.018

2.77 ± 1.03

0.95 ± 0.39

0.98 ± 0.30

U87

0.180 ± 0.031

0.015 ± 0.004

12.35 ± 2.45

0.122 ± 0.030

0.019 ± 0.004

6.23 ± 1.18

0.96 ± 0.21

0.94 ± 0.17

HEPG2

0.161 ± 0.042

0.021 ± 0.006

7.51 ± 1.61

0.272 ± 0.076

0.025 ± 0.011

11.08 ± 3.26

1.28 ± 0.03

1.31 ± 0.32