From: Cardiac-sparing radiotherapy for locally advanced non-small cell lung cancer
Coverage measure (IDEAL-CRT limit) | At baseline | After MDHeart reduction | After VHeart-50-Gy reduction | After VLAwall-63-Gy reduction |
---|---|---|---|---|
DPTV-90%* (≥ 95% prescribed dose) | 98.6% (96.7, 99.0%) | 97.9% (95.7, 98.9%) p = 6 × 10–4 | 98.0% (96.3, 98.9%) p = 2 × 10–4 | 98.4% (95.3, 99.0%) p = 0.31 |
DPTV-98% (≥ 90% prescribed dose) | 96.7% (92.4, 97.9%) | 95.0% (90.7, 97.3%) p = 4 × 10–4 | 95.1% (91.5, 97.5%) p = 2 × 10–4 | 96.4% (90.4, 97.7%) p = 0.09 |
DCTV-99% (≥ 95% prescribed dose) | 98.0% (96.5, 98.6%) | 97.6% (95.7, 98.4%) p = 7 × 10–3 | 97.7% (96.1, 98.4%) p = 8 × 10–3 | 97.9% (95.6, 98.6%) p = 0.27 |
DPTV-99.5% (non-protocol measure) | 95.2% (86.5, 96.9%) | 91.9% (86.7, 96.4%) p = 1 × 10–3 | 92.5% (86.0, 96.4%) p = 3 × 10–4 | 94.6% (86.9, 96.6%) p = 0.09 |